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Table 2 Adverse Events during Chemoradiation (n = 91)a

From: A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis

 

Grade 1

Grade 2

Grade 3

Leukopenia

24 (26.37%)

11 (12.09%)

-

Neutropenia

1 (1.10%)

6 (6.59%)

-

Anemia

33 (36.26%)

7 (7.69%)

2 (2.20%)

Thrombocytopenia

6 (6.59%)

-

-

Fatigue

17 (18.68%)

-

-

Anorexia

43 (47.25%)

4 (4.40%)

1 (1.10%)

Nausea

41 (45.05%)

1 (1.10%)

-

Constipation

11 (12.09%)

1 (1.10%)

-

Diarrhea

11 (12.09%)

4 (4.40%)

10 (10.99%)

Stomatitis

10 (10.99%)

5 (5.49%)

1 (1.10%)

Abdominal pain

35 (38.46%)

7 (7.69%)

2 (2.20%)

Anal pain

13 (14.29%)

5 (5.49%)

-

  1. aAdverse events were graded according to Common Terminology Criteria of Adverse Events version 3.0. There were no grade 4 or 5 adverse events
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Radiation Oncology

ISSN: 1748-717X

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