Table 2 Selected existing reports describing dose constraints to the kidney during pancreatic SBRT. SBRT, stereotactic body radiotherapy; SIB, simultaneous integrated boost
Study | Treatment regimen/dose | Dose-volume constraint |
|---|---|---|
Koong et al. [4] | 45 Gy/25 fractions + 25 Gy single-fraction SBRT | 70% of each kidney <15 Gy |
Chang et al. [5] | 79% patients with 25 Gy single-fraction SBRT; 21% patients with preceding 45–54 Gy/25–30 fractions | 75% of each kidney <5 Gy |
Chuong et al. [6] | 25–30 Gy/5 fractions, SIB to involved perivascular areas to 35–50 Gy | Kidney mean dose <10 Gy |
Su et al. [7] | 30–36 Gy/3 fractions | 1/3 of kidney volume <15 Gy |
Herman et al. [8] | 33 Gy/5 fractions | 75% of both kidneys <12 Gy |