Table 3 Univariate analysis of prognostic factors (except for SVZ-dosimetric data) for time-to-progression (TTP) and overall survival (OS) in patients with newly diagnosed glioblastoma
From: Subventricular zones: new key targets for glioblastoma treatment
Prognostic factors | Median TTP (months) | p value | Median OS (months) | p value |
|---|---|---|---|---|
Age | ||||
 < 60 years | 5.2 | 0.651 | 24.7 | 0.914 |
 ≥ 60 years | 6.4 |  | 14.4 |  |
Gender | ||||
 Male | 4.8 | 0.406 | 20.5 | 0.603 |
 Female | 9.1 |  | 26.2 |  |
ECOG performans status | ||||
 0–1 | 5.3 | 0.366 | 24.7 | 0.465 |
 2–4 | 6.7 |  | 14.6 |  |
Multilobar lesion | ||||
 No | 5.6 | 0.826 | 20.7 | 0.896 |
 Yes | 6.4 |  | 22.7 |  |
Tumor SVZ contact | ||||
 Yes | 4.6 | 0.002 | 18.7 | 0.014 |
 No | 12.9 |  | 41.7 |  |
MGMT status | ||||
 Methylated | 5.3 | 0.245 | 24.7 | 0.281 |
 Unmethylated | 6.4 |  | 20.5 |  |
Extent of resection | ||||
 GTR/NTR | 5.6 | 0.669 | 25.1 | 0.598 |
 STR | 6.4 |  | 18.7 |  |