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Table 2 Dosimetric endpoints for ibIMRT and sIMRT Plans

From: Reducing radiation dose to normal brain through a risk adapted dose reduction protocol for patients with favourable subtype anaplastic glioma

Endpoint

ibIMRT (median and range)

sIMRT (median and range)

P value

PTVhr Dose (Median)

59.9Gy (58.0–60.4Gy)

59.8Gy (58.1–61.6Gy)

p = 0.33

PTVsr Dose (Median)

56.0Gy (54.1–57.0Gy)

59.8Gy (58.1–61.6Gy)

P < 0.001

V40 (volume of brain receiving 40Gy)

14.9% (11.8–30.4%)

18.3% (14.5–29.2%)

p = 0.005

V20 (volume of brain receiving 20Gy)

45.8% (29.2–71.1%)

52.6% (35.2–68.4%)

p = 0.001

Mean Dose to Brain

22.3Gy (16.3–29.9)

24.5Gy (19.3–30.9)

p = 0.007