Table 1 Clinical characteristics and survival-related factors of 232 patients with ES-SCLC in univariate and multivariate analysis
Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|
Patients, n (%) | MST, mo | P | OR (95% CI) | P | ||
Age, y | ≥65 | 64 (27.6) | 13.0 | 0.313 | ||
<65 | 168 (72.4) | 13.8 | ||||
Gender | Male | 182 (78.4) | 12.4 | 0.027 | 0.798 (0.510–1.248) | 0.323 |
Female | 50 (21.6) | 19.3 | ||||
KPS | ≥80 | 215 (92.7) | 13.8 | 0.296 | ||
<80 | 17 (7.3) | 9.7 | ||||
Smoking | Yes | 188 (81.0) | 12.8 | 0.191 | ||
No | 44 (19.0) | 16.3 | ||||
PCI | Yes | 26 (11.2) | 22.3 | 0.010 | 0.587 (0.340–1.015) | 0.057 |
No | 206 (88.8) | 12.1 | ||||
Distant metastasis | Yes | 200 (86.2) | 14.7 | 0.108 | ||
No | 32 (13.8) | 18.9 | ||||
Number of metastases ≥ 2 | Yes | 151 (65.1) | 12.1 | 0.037 | 1.443 (0.860–2.422) | 0.165 |
No | 81 (34.9) | 15.8 | ||||
Weight loss | Yes | 27 (11.6) | 11.6 | 0.304 | ||
No | 205 (88.4) | 13.8 | ||||
TRT | Yes | 187 (80.6) | 15.0 | <0.001 | 0.374 (0.262–0.532) | <0.001 |
No | 45 (19.4) | 8.3 | ||||
TRT | ERT | 65 (28.0) | 14.6 | 0.720 | 1.185 (0.814–1.727) | 0.376 |
LRT | 122 (52.6) | 15.4 | ||||