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Table 3 Multivariate analysis for overall survival, initial site control and new site control

From: Clinical outcomes of gastrointestinal brain metastases treated with radiotherapy

Characteristic HR (95% CI) P-value
Overall survival   
 Age 0.99 (0.95–1.02) 0.451
 ECOG 1.63 (0.69–3.86) 0.263
 >2 brain metastases 0.53 (0.12–2.25) 0.388
 Active extracranial disease 3.02 (0.62–14.79) 0.173
 Intracranial Surgery prior to RT 0.62 (0.24–1.61) 0.326
 Treatment WBRT 1.39 (0.45–4.22) 0.566
Initial site control   
 Total Dose 0.69 (0.31–1.55) 0.372
 Treatment WBRT 1.95 (0.68–5.6) 0.212
 Intracranial Surgery prior to RT 0.47 (0.16–1.36) 0.164
New site control   
 Total Dose 3.98 (1.13–14.07) 0.032*
 Treatment WBRT 0.05 (0.01–0.35) 0.002*
 Active extracranial disease 11.4 (1.54–84.52) 0.017*
  1. Abbreviations: CI confidence interval, HR hazard ratio, ECOG Eastern Cooperative Oncology group
  2. Statistically significant results indicated by *