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Table 1 Patient characteristics

From: Clinical outcomes of gastrointestinal brain metastases treated with radiotherapy

Treatment
  WBRT SRS Total  
  (n = 12) (n = 21) (n = 33) P-value
Median age (range) 62 (41 ~ 76) 62 (29 ~ 83) 62 (29 ~ 83) 0.963
Median interval between cancer diagnosis and brain metastases (range) 422.5 (0 ~ 2155) 905 (22 ~ 1668) 542 (0 ~ 2155) 0.779
Brain metastases at initial presentation [N (%)]     
 Yes 2 (100) 0 (0) 2 0.125
 No 10 (32) 21 (68) 31  
Intracranial surgery prior to radiation therapy [N (%)]     
 No 7 (50) 7 (50) 14 0.273
 Yes 5 (26) 14 (74) 19  
Primary site [n (%)]     
 Colon 4 (24) 13 (76) 17 0.247
 Esophagus 3 (50) 3 (50) 6  
 Other 4 (67) 2 (33) 6  
 Rectum 1 (25) 3 (75) 4  
BMs [n (%)]     
 ≤2 4 (17) 19 (83) 23 0.001*
 >2 8 (80) 2 (20) 10  
ECOG [N (%)]     
 Unknown 0 (0) 1 (100) 1 0.273
 ≤1 8 (50) 8 (50) 16  
 >1 4 (25) 12 (75) 16  
RPA class [N (%)]     
 Unknown 0 (0) 1 (100) 1 0.144
 I and II 8 (53) 7 (47) 15  
 III 4 (24) 13 (76) 17  
  1. Abbreviations: WBRT whole brain radiation therapy, SRS stereotactic radiosurgery, BMs brain metastases, ECOG Eastern Cooperative Oncology Group, RPA recursive partitioning analysis
  2. Statistically significant results indicated by *