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Table 1 Patient characteristics

From: Clinical outcomes of gastrointestinal brain metastases treated with radiotherapy

Treatment

 

WBRT

SRS

Total

 
 

(n = 12)

(n = 21)

(n = 33)

P-value

Median age (range)

62 (41 ~ 76)

62 (29 ~ 83)

62 (29 ~ 83)

0.963

Median interval between cancer diagnosis and brain metastases (range)

422.5 (0 ~ 2155)

905 (22 ~ 1668)

542 (0 ~ 2155)

0.779

Brain metastases at initial presentation [N (%)]

    

 Yes

2 (100)

0 (0)

2

0.125

 No

10 (32)

21 (68)

31

 

Intracranial surgery prior to radiation therapy [N (%)]

    

 No

7 (50)

7 (50)

14

0.273

 Yes

5 (26)

14 (74)

19

 

Primary site [n (%)]

    

 Colon

4 (24)

13 (76)

17

0.247

 Esophagus

3 (50)

3 (50)

6

 

 Other

4 (67)

2 (33)

6

 

 Rectum

1 (25)

3 (75)

4

 

BMs [n (%)]

    

 ≤2

4 (17)

19 (83)

23

0.001*

 >2

8 (80)

2 (20)

10

 

ECOG [N (%)]

    

 Unknown

0 (0)

1 (100)

1

0.273

 ≤1

8 (50)

8 (50)

16

 

 >1

4 (25)

12 (75)

16

 

RPA class [N (%)]

    

 Unknown

0 (0)

1 (100)

1

0.144

 I and II

8 (53)

7 (47)

15

 

 III

4 (24)

13 (76)

17

 
  1. Abbreviations: WBRT whole brain radiation therapy, SRS stereotactic radiosurgery, BMs brain metastases, ECOG Eastern Cooperative Oncology Group, RPA recursive partitioning analysis
  2. Statistically significant results indicated by *