The use of dose-escalated radiation for locally advanced non-small cell lung cancer in the U.S., 2004–2013

Radiation Oncology

Table 2 Patient and hospital characteristics for the NODA primary analytic cohort (excluding 2013 data) and the NCDB cohort without RT dose exclusions

Study sample characteristics	NODA 2004–2012^a	NCDB 2004–2012 without RT dose exclusions^a	P value*
Study sample characteristics	No. (%)	No. (%)	P value*
Age
≤ 67 yo	829 (51.5)	12,619 (54.0)	0.05
> 67 yo	781 (48.5)	10,741 (46.0)
Sex
Male	943 (58.6)	13,422 (57.5)	0.38
Female	667 (41.4)	9938 (42.5)
Race
White	1395 (86.6)	19,841 (84.9)	0.03
Non-white	202 (12.5)	3377 (14.5)
Missing	13 (0.8)	142 (0.6)
Histology
Squamous	681 (42.3)	9680 (41.4)	0.50
Non-Squamous	929 (57.7)	13,680 (58.6)
T-stage^b
T0-2	1074 (66.7)	15,418 (66.0)	0.06
T3	499 (31.0)	7942 (34.0)
Missing	37 (2.3)	0 (0%)
Charlson/Deyo Score
0	1063 (66.0)	14,695 (62.9)	0.03
1	400 (24.9)	6209 (26.6)
2+	147 (9.1)	2456 (10.5)
Hospital type^c
Community	1316 (81.7)	17,207 (73.7)	<0.0001
Academic	294 (18.3)	6153 (26.3)
Hospital setting^c
Metro	1338 (83.1)	17,204 (73.6)	<0.0001
Non-metro	272 (16.9)	5210 (22.3)
Missing	0 (0)	946 (4.0)

^aThe NODA cohort was defined by year of treatment start and the NCDB cohort was defined by year of diagnosis. The NODA cohort was filtered using RT dose criteria but the NCDB cohort was not in order to preserve its representativeness of the national lung cancer population. *Chi-square test. Missing data was excluded from Chi-Square comparison. ^bT –stage comparison was done only for patients staged according to AJCC version 6 and missing data was excluded from Chi-Square comparison. ^cHospital characteristics are those of the diagnosing hospital, not treating institution

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