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Table 2 Selected studies of Intraoperative Radiotherapy in locally advanced/unresectable pancreatic cancer

From: Intraoperative radiation therapy (IORT) in pancreatic cancer

Studies Number IORT Dose (Gy) Local Recurrence Overall Survival (Median)
Roldan et al. [31] 159 20   
122 EBRT   52% 12.6 month
37 EBRT and IORT   18% 13.4 month
Tepper et al. [39] 51
EBRT and IORT
20 Not assessable 9 month
Willet et al. [40]
Cai et al. [41]
194
EBRT and IORT
15–25 2 y
59%
12 month
Mohiddin et al. [48] 49
EBRT and IORT
10–20 29% 16 month
Schuricht et al. [49] 105
76 EBRT and IORT
29 EBRT
15–20 30% 15–20 month
Keane et al. [45] 85 (locally advanced/Borderline resectable) 10–20   
26 IORT    20.5 month
49 resected    
 24 surgery and IORT    35.1 month
 25 surgery    301.1 month