Table 2 Selected studies of Intraoperative Radiotherapy in locally advanced/unresectable pancreatic cancer

Roldan et al. [31]

159

20

122 EBRT

52%

12.6 month

37 EBRT and IORT

18%

13.4 month

Tepper et al. [39]

51

EBRT and IORT

20

Not assessable

9 month

Willet et al. [40]

Cai et al. [41]

194

EBRT and IORT

15–25

2 y

59%

12 month

Mohiddin et al. [48]

49

EBRT and IORT

10–20

29%

16 month

Schuricht et al. [49]

105

76 EBRT and IORT

29 EBRT

15–20

30%

15–20 month

Keane et al. [45]

85 (locally advanced/Borderline resectable)

10–20

26 IORT

20.5 month

49 resected

 24 surgery and IORT

35.1 month

 25 surgery

301.1 month