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Table 1 Disease control and survival in locally advanced colon cancer, Mayo Clinic results

From: Intraoperative radiation therapy for colon and rectal cancers: a clinical review

Group

# Patients

5-year LR

5-year DM

5-year OS

R0 resection

50

10%

~30%

66%

R1 resection

18

54%

~57%

47%

R2 resection

35

79%

~68%

23%

  

p < 0.0001

p = 0.002

p = 0.0009

EBRT > 50 Gy

73

36%

-

50%

EBRT ≤ 50 Gy

30

50%

-

45%

  

p = 0.18

 

p = 0.16

R1-2 + IOERT

9

11%

~12%

76%

R1-2, no IOERT

44

82%

~76%

26%

  

p = 0.02

p = 0.01

p = 0.04

  1. Abbreviations: EBRT external beam radiation therapy, LR local relapse, DM distant metastases, OS overall survival, IOERT intraoperative electron radiation therapy