Clinical outcomes of stage I and IIA non-small cell lung cancer patients treated with stereotactic body radiotherapy using a real-time tumor-tracking radiotherapy system

Table 4 Univariate and multivariate analysis results of local control rates

Variables		Local Control Rates (%)			Univariate Analysis	Multivariate Analysis
Variables		n	2-year	3-year	p-value	HR (95%CI)	p-value
T stage	T1a + T1b	195	84	79	0.1263	-	0.5903
T stage	T2a + T2b	91	74	64		1.173 (0.647–2.076)
Histology	Adenocarcinoma	185	87	80	0.0002	-	0.0044
Histology	SCC	80	65	62		2.366 (1.311–4.301)
Gender	Female	69	88	85	0.0595	-	0.2307
Gender	Male	217	79	71		1.595 (0.751–3.700)
Location	Upper and Middle	167	82	76	0.8487	-	0.8845
Location	Lower	119	79	73		1.042 (0.591–1.808)
BED (10) IC (Gy)	≥ 90	267	84	78	0.0001	-	0.0017
BED (10) IC (Gy)	< 90	19	49	42		3.465 (1.655–6.706)
Margins from GTV to PTV (mm)	≥ 10	158	81	71	0.8043	-	0.8723
Margins from GTV to PTV (mm)	< 10	124	80	78		1.047 (0.589–1.833)

BED biologically effective dose, CI confidence interval, GTV gross tumor volume, HR hazard ratio, IC isocenter, LC local control, PTV planning target volume, SCC squamous cell carcinoma

ISSN: 1748-717X