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Table 2 Grade 3–4 acute and late toxic effects

From: PET/CT-guided dose-painting versus CT-based intensity modulated radiation therapy in locoregional advanced nasopharyngeal carcinoma

Adverse events

PET/CT-guided DP-IMRT

CT-based IMRT

p value*

No. of patients (%)

No. of patients (%)

Acute adverse events

 Anemia

1 (1.0)

2 (1.8)

0.54

 Neutropenia

8 (7.9)

11 (9.8)

0.63

 Leukopenia

15 (14.9)

18 (16.1)

0.85

 Thrombocytopenia

1 (1.0)

1 (0.9)

0.73

 Liver dysfunction

0

0

..

 Nephrotoxicity

0

0

..

 Nausea

14 (13.9)

17 (15.2)

0.85

 Vomiting

10 (9.9)

13 (11.6)

0.83

 Mucositis

31 (30.7)

34 (32.1)

0.77

 Dermatitis

9 (8.9)

12 (10.7)

0.82

 Dysphagia or odynophagia

3 (2.9)

5 (4.5)

0.72

 Dry mouth

3 (2.9)

6 (5.3)

0.50

 Ototoxicity

0

1 (0.9)

0.53

Late adverse events

 Skin fibrosis

0

1 (0.9)

0.53

 Dry mouth

0

0

..

 Ototoxicity

0

1 (0.9)

0.53

 Trismus

0

0

..

 Nasopharyngeal ulceration

0

0

..

  1. *p values were calculated by the χ 2 test