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Table 3 Dose metrics for PTVs; median and ranges and statistical outcomes for different energies and arc arrangements for prostate and pelvic nodes (PPLN) plans

From: Class solutions for SABR-VMAT for high-risk prostate cancer with and without elective nodal irradiation

Structure

 

2FA

2PA300

Volume (cc)

 

10 F

6 F

6MV

10 F

6 F

6MV

 

HI

1.05

1.05

1.05

1.05

1.05

1.05

  

(1.05–1.05)

(1.05–1.05)

(1.05–1.05)

(1.05–1.05)

(1.05–1.05)

(1.05–1.05)

 

CI

1.21

1.21

1.22

1.23 ɫ

1.23

1.22

  

(1.20–1.22)

(1.18–1.22)

(1.20–1.22)

(1.21–1.24)

(1.21–1.24)

(1.21–1.24)

 

CN

0.91

0.91

0.91

0.91

0.91

0.91

  

(0.89–0.92)

(0.90–0.92)

(0.91–0.92)

(0.88–0.92)

(0.89–0.92)

(0.89–0.92)

 

R50

4.21

4.43*

4.50*

4.31

4.63*

4.64*

  

(4.06–4.39)

(4.31–4.60)

(4.42–4.67)

(4.17–4.43)

(4.48–4.81)

(4.57–4.79)

 

R25

8.65

9.02*

9.19*

8.80

9.09

9.19*

  

(8.32–9.07)

(8.63–9.63)

(8.69–9.72)

(8.48–9.24)

(8.70–9.43)

(8.83–9.81)

PTV(P)

67.2

D98% (Gy)

35.7

35.8

35.9

35.7

35.8

35.8

(54.6–92.8)

 

(35.3–36.1)

(35.4–36.0)

(35.5–36.1)

(35.3–36.0)

(35.3–35.9)

(35.4–35.9)

 

D2% (Gy)

42.0

42.0

42.0

42.0

42.0

42.1

  

(42.0–42.1)

(42.0–42.1)

(42.0–42.1)

(42.0–42.1)

(42.0–42.1)

(42.0–42.1)

PTV(SV/LN)

796.2

D98%(Gy)

24.2

24.2

24.2

24.1

24.0

24.1

(746.4 − 855.9)

 

(24.1–24.3)

(24.1–24.2)

(24.2–24.3)

(24.0–24.2)

(23.9–24.0)

(24.1–24.3)

 

D2% (Gy)¥

26.6

26.6

24.7

26.6

26.7

26.7

  

(26.6–26.7)

(26.5–26.7)

(26.5–26.7)

(26.6–26.8)

(26.6–26.8)

(26.6–26.8)

  1. Abbreviations: FA full arc, PA300 300° partial arc, HI homogeneity index, CI conformity index, CN conformation number, R 50 , R 25 intermediate and low dose spillage (evaluated for PTV(SV/LN) receiving 25Gy), D98% = near minimum dose, D2% = near maximum dose. * = significantly different from 10 F plans (same arc arrangement), ɫ = significantly different from 10 F (FA) plans. ¥ assessed for a structure [(PTV(SV/LN)) – (PTV(P) = 10 mm]
  2. p ≤ 0.01 considered statistically significant (*, ɫ)