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Table 4 Predictors of grade ≥2 late observer-rated dysphagia (logistic regression)

From: Contribution of submandibular gland and swallowing structure sparing to post-radiation therapy PEG dependence in oropharynx cancer patients treated with split-neck IMRT technique

Variable (mean doses in Gy)

Univariate

Multivariate

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Contralateral submandibular gland dose

1.06 (1.02–1.10)

0.004

1.03 (0.98–1.09)

0.29

T4 tumor stage

5.99 (1.77–24.18)

0.006

4.60 (1.17–21.16)

0.04

Superior pharyngeal constrictor dose

1.27 (1.09–1.56)

0.009

1.15 (0.98–1.42)

0.12

Oral cavity dose

1.08 (1.01–1.16)

0.03

1.02 (0.94–1.12)

0.62

Bilateral nodal involvement

3.26 (1.02–11.18)

0.05

1.45 (0.28–7.56)

0.65

Glottic/supraglottic larynx dose

1.06 (1.00–1.12)

0.06

  

Parotid glands mean dose

1.06 (0.99–1.15)

0.11

  

Inferior pharyngeal constrictor dose

1.04 (0.99–1.09)

0.13

  

Middle pharyngeal constrictor dose

1.08 (0.98–1.21)

0.15

  

Cricopharyngeal muscle dose

1.02 (0.98–1.07)

0.35

  

Age

1.02 (0.95–1.10)

0.56

  

Esophageal inlet muscles dose

1.01 (0.97–1.05)

0.63

  
  1. Statistically significant values are given in bold