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Table 3 Predictors of time to freedom from PEG tube dependence (Cox proportional hazards model). Lower hazard ratio indicates later PEG tube removal

From: Contribution of submandibular gland and swallowing structure sparing to post-radiation therapy PEG dependence in oropharynx cancer patients treated with split-neck IMRT technique

Variable (mean doses in Gy) Univariate Multivariate
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Contralateral submandibular gland dose 0.97 (0.95–0.98) <0.0001 0.98 (0.95–1.00) 0.052
Middle pharyngeal constrictor dose 0.92 (0.88–0.96) 0.0002 0.95 (0.89–1.02) 0.18
Superior pharyngeal constrictor dose 0.95 (0.92–0.98) 0.003 0.98 (0.93–1.03) 0.38
Glottic/supraglottic larynx dose 0.97 (0.94–0.99) 0.007 1.02 (0.98–1.07) 0.40
Esophageal inlet muscles dose 0.98 (0.97–1.00) 0.03 0.99 (0.97–1.01) 0.39
Oral cavity dose 0.97 (0.95–0.99) 0.03 1.00 (0.97–1.04) 0.86
Inferior pharyngeal constrictor dose 0.98 (0.96–1.00) 0.09   
T4 tumor stage 0.69 (0.42–1.15) 0.16   
Parotid glands mean dose 0.98 (0.94–1.02) 0.24   
Bilateral nodal involvement 0.77 (0.47–1.27) 0.31   
Cricopharyngeal muscle dose 0.99 (0.97–1.01) 0.34   
Age 1.00 (0.97–1.03) 0.96   
  1. Statistically significant values are given in bold