| |
Univariate analysis
|
Multivariate analysis
|
Bootstrapping (170 rep)
|
|---|
|
Acute GIa toxicity G ≥ 1 / N
|
ORc
|
95 % CId
|
p-value
|
Acute GI toxicity G ≥ 1 / N
|
OR
|
95 % CI
|
p-value
|
95 % CI
|
p-value
|
|---|
| |
115/178
|
|---|
|
rAUC25-50
b rectum
|
|
Liu/Youden cutting methods
|
|
< =794 cc.Gy
|
29/59
|
1
| |
0.002
|
28 / 58
|
1
| |
0.020
| |
0.019
|
|
> 794 cc.Gy
|
88/121
|
2.76
|
[1.44;5.28]
| |
87 / 120
|
2.51
|
[1.16;5.46]
| |
[1.16;5.42]
| |
|
Adjustment variables
|
|
Age
|
|
< 70 years
|
57/82
|
1
| |
0.247
|
57 / 82
|
1
| |
0.233
| |
0.226
|
|
> = 70 years
|
60/ 98
|
0.69
|
[0.37;1.29]
| |
58 / 96
|
0.67
|
[0.35;1.29]
| |
[0.35;1.28]
| |
|
TURPe
|
|
No
|
95/143
|
1
| |
0.305
|
95 / 143
|
1
| |
0.423
| |
0.459
|
|
Yes
|
20/35
|
0.67
|
[0.32;1.43]
| |
20 / 35
|
0.72
|
[0.33;1.59]
| |
[0.31;1.7]
| |
|
HTf
|
|
No
|
65/104
|
1
| |
0.411
|
64 / 103
|
1
| |
0.757
| |
0.755
|
|
Yes
|
52/76
|
1.3
|
[0.7;2.43]
| |
51 / 75
|
1.11
|
[0.57;2.16]
| |
[0.57;2.15]
| |
|
Rectum Volume (cc) per unit
| |
1
| |
0.041
| |
1
| |
0.558
| |
0.570
|
| |
1.01
|
[1;1.02]
| | |
1
|
[0.99;1.01]
| |
[0.99;1.01]
| |
-
agastrointestinal; bArea Under the Curve of rectal DHV between 25 and 50Gy, codds ratio; d95 % confidence interval;e transurethral resection of the prostate; fhormonotherapy
