Table 2 Evaluation of relationship between DVSE and acute gastrointestinal toxicity using univariate logistic regression analysis
Median [range] | All patients | Patients with acute toxicities Gb = 0 | Patients with acute toxicities G ≥ 1 | p-value |
|---|---|---|---|---|
n = 180 | n = 63 | n = 117 | ||
Rectum volumes expressed in % | ||||
V25a | 68 [27;100] | 69.6 [27;100] | 67.7 [31.6;100] | 0.799 |
V30 | 60.9 [24.2;100] | 61.6 [24.2;100] | 60.7 [25.5;100] | 0.860 |
V35 | 51.9 [21;100] | 51.7 [21.8;99.6] | 52.1 [21;100] | 0.726 |
V40 | 44 [17.6;96.7] | 44.3 [19.7;85.3] | 43.9 [17.6;96.7] | 0.638 |
V45 | 35.2 [13.1;82.2] | 37.1 [15.5;62.8] | 34.8 [13.1;82.2] | 0.704 |
V50 | 27.8 [8;74.6] | 28.3 [9.3;52.9] | 27.7 [8;74.6] | 0.766 |
V55 | 22.4 [5.4;51.2] | 23 [5.4;43.6] | 22.3 [6.1;51.2] | 0.875 |
V60 | 17.2 [2.7;40.8] | 17.6 [2.7;35.1] | 17 [3.4;40.8] | 0.918 |
V65 | 11.8 [1;29.5] | 12.6 [1;29.5] | 11.5 [1.2;26.5] | 0.582 |
V70 | 7.3 [0;23.1] | 7.8 [0;23.1] | 6.7 [0;19.8] | 0.217 |
V75 | 0.9 [0;11.4] | 1.5 [0;11.4] | 0.7 [0;9.1] | 0.124 |
Rectum volumes expressed in cc | ||||
V25 | 53.5 [20.1;223] | 48.8 [20.1;114] | 57 [20.6;223] | 0.039 |
V30 | 47.5 [19.5;180.2] | 42.8 [19.5;99.8] | 50.9 [19.8;180.2] | 0.045 |
V35 | 41.7 [16.7;150] | 37.8 [16.7;86] | 42.6 [17.4;150] | 0.035 |
V40 | 36.1 [11;120.8] | 31.9 [11;79] | 37.4 [13.9;120.8] | 0.025 |
V45 | 29.8 [8;101.9] | 25.8 [8;69.1] | 31.6 [10.2;101.9] | 0.018 |
V50 | 24.1 [5.9;77] | 21.1 [5.9;58.1] | 25 [7.6;77] | 0.035 |
V55 | 19 [4.4;56.4] | 17.9 [4.4;47.8] | 19.7 [5.8;56.4] | 0.069 |
V60 | 14.6 [2.4;43.6] | 13.1 [2.4;36.3] | 15.2 [3.1;43.6] | 0.17 |
V65 | 10.2 [0.9;36.8] | 9.9 [0.9;28.7] | 11 [1.3;36.8] | 0.387 |
V70 | 5.7 [0;29.5] | 5.8 [0;20.2] | 5.7 [0;29.5] | 0.853 |
V75 | 0.8 [0;16.2] | 0.9 [0;8] | 0.6 [0;16.2] | 0.232 |
rAUC25–50 (cc. Gy) c | 972.5 [388.5;3305.3] | 835.7 [394.3;2008.8] | 1002.4 [388.5;3305.3] | 0.028 |