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Table 4 A summary of the average dosimetric parameters for \(\mathbb {P}^{\text {WH}}\), \(\mathbb {P}^{\text {RF}}\), \(\mathbb {P}^{\text {WF}}\) for brachytherapy

From: Radiomics based targeted radiotherapy planning (Rad-TRaP): a computational framework for prostate cancer treatment planning with MRI

Parameter Whole gland homogeneous (\(\mathbb {P}^{\text {WH}}\)) Whole gland with a focal boost (\(\mathbb {P}^{\text {WF}}\)) Focal (\(\mathbb {P}^{\text {RF}}\)) (\(\mathbb {P}^{\text {WF}}-\mathbb {P}^{\text {WH}}\)) (\(\mathbb {P}^{\text {RF}}-\mathbb {P}^{\text {WH}}\))
Number of needles 22.00 22.10 17.20 0.10 -4.80
Number of seeds 74.80 74.20 43.00 -0.60 -31.80
Prostate
D 90 (Gy) 181.14 185.56 64.11 4.41 -117.03
V 100 (%) 99.80 99.85 56.17 0.05 -43.63
V 150 (%) 58.11 61.47 40.72 3.36 -17.38
V 200 (%) 22.51 23.61 25.76 1.10 3.25
Urethra
D 10 (Gy) 192.17 195.62 182.82 3.46 -9.34
V 100 (%) 96.55 96.62 41.38 0.07 -55.1
Rectum
D 1c c. (Gy) 119.81 121.77 116.79 1.96 -3.02
D 2c c. (Gy) 102.00 102.85 92.40 0.85 -9.60
V 100 (%) 1.14 1.41 1.63 0.27 0.49
Bladder
D 2c c. (Gy) 105.20 102.07 46.96 -3.13 -58.24
PTV
D 90 (Gy) 174.16 174.08 248.51 -0.09 74.35
V 100 (%) 99.10 98.28 99.99 -0.82 0.90
V 150 (%) 55.05 55.25 97.99 0.20 42.94
V 200 (%) 21.67 21.64 76.21 -0.02 54.54
  1. It can be observed that \(\mathbb {P}^{\text {RF}}\) resulted in a better coverage of the PTV, reduction in the unneeded dosage to prostate and surrounding regions, and a marked reduction in the number of needles and seeds (highlighted in bold-face)