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Table 4 A summary of the average dosimetric parameters for \(\mathbb {P}^{\text {WH}}\), \(\mathbb {P}^{\text {RF}}\), \(\mathbb {P}^{\text {WF}}\) for brachytherapy

From: Radiomics based targeted radiotherapy planning (Rad-TRaP): a computational framework for prostate cancer treatment planning with MRI

Parameter

Whole gland homogeneous (\(\mathbb {P}^{\text {WH}}\))

Whole gland with a focal boost (\(\mathbb {P}^{\text {WF}}\))

Focal (\(\mathbb {P}^{\text {RF}}\))

(\(\mathbb {P}^{\text {WF}}-\mathbb {P}^{\text {WH}}\))

(\(\mathbb {P}^{\text {RF}}-\mathbb {P}^{\text {WH}}\))

Number of needles

22.00

22.10

17.20

0.10

-4.80

Number of seeds

74.80

74.20

43.00

-0.60

-31.80

Prostate

D 90 (Gy)

181.14

185.56

64.11

4.41

-117.03

V 100 (%)

99.80

99.85

56.17

0.05

-43.63

V 150 (%)

58.11

61.47

40.72

3.36

-17.38

V 200 (%)

22.51

23.61

25.76

1.10

3.25

Urethra

D 10 (Gy)

192.17

195.62

182.82

3.46

-9.34

V 100 (%)

96.55

96.62

41.38

0.07

-55.1

Rectum

D 1c c. (Gy)

119.81

121.77

116.79

1.96

-3.02

D 2c c. (Gy)

102.00

102.85

92.40

0.85

-9.60

V 100 (%)

1.14

1.41

1.63

0.27

0.49

Bladder

D 2c c. (Gy)

105.20

102.07

46.96

-3.13

-58.24

PTV

D 90 (Gy)

174.16

174.08

248.51

-0.09

74.35

V 100 (%)

99.10

98.28

99.99

-0.82

0.90

V 150 (%)

55.05

55.25

97.99

0.20

42.94

V 200 (%)

21.67

21.64

76.21

-0.02

54.54

  1. It can be observed that \(\mathbb {P}^{\text {RF}}\) resulted in a better coverage of the PTV, reduction in the unneeded dosage to prostate and surrounding regions, and a marked reduction in the number of needles and seeds (highlighted in bold-face)