Pancreatic cancer adjuvant radiotherapy target volume design: based on the postoperative local recurrence spatial location

Table 6 Comparison of dosimetric parameters between the proposed plan and RTOG 0848 plan in 4 simulated cases (cGy)

	The proposed plan			RTOG 0848			The proposed plan			RTOG 0848
	D99	D50	D1	D99	D50	D1	D99	D50	D1	D99	D50	D1
	Case 1						Case 2
PTV_modified (RTOG0848)				5010	5132	5303				5004	5101	5243
left kidney	251	1004	2234	1456	1797	3080	41	505	2182	138	1750	4625
right kidney	65	374	1601	578	1527	5299	40	392	2241	123	1477	4749
Stomach	92	676	1956	293	1898	4392	69	599	1654	225	2123	4865
Small intestine	66	699	1904	360	2801	5267	104	739	1614	382	3238	5147
Liver	29	526	3211	117	2477	5209	11	270	2737	75	1493	5137
Spinal cord	2	131	702	9	675	4564	2	72	697	1	275	3728
Large bowel	0	3	1420	0	9	5169	0	3	1246	0	22	2658
Proximal large bowel	74	628	1879	458	2166	5266	72	284	1739	260	1030	3845
Proximal stomach	104	688	1959	339	1915	4405	99	662	1671	389	2247	4850
Proximal small intestine	86	847	1937	643	3021	5276	104	739	1614	368	3025	5243
PTV-80_modified	2989	3571	3947				2978	3581	3934
PTV-90_modified	2461	3362	3923				2457	3350	3904
	Case 3						Case 4
PTV_modified (RTOG0848)				5000	5132	5230				4995	5136	5249
left kidney	57	654	1629	271	1834	3618	90	836	1975	1312	1904	3821
right kidney	76	823	1904	404	1682	4443	68	631	1890	916	1717	4036
Stomach	19	128	1481	104	1108	5100	52	134	942	162	510	3197
Small intestine	37	500	1570	273	1874	5140	30	379	1537	364	1919	5206
Liver	19	222	1801	118	1576	5108	11	230	2116	103	1436	5172
Spinal cord	2	96	752	21	868	3624	1	67	738	4	485	3602
Large bowel	0	192	1500	0	1064	5009	0	5	1531	0	89	4366
Proximal large bowel	83	747	1582	566	2083	5052	62	583	1746	697	2400	4807
Proximal stomach	81	490	1600	733	2571	5112	110	394	1003	492	1699	3077
Proximal small intestine	70	793	1634	480	2235	5187	82	621	1716	591	2105	5257
PTV-80_modified	3110	3596	3949				2990	3557	3940
PTV-90_modified	2380	3344	3924				2478	3350	3922

Abbreviations: D99 the dose 99 % of the volume received, D50 the dose 50 % of the volume received, D1 the dose 1 % of the volume received, PTV-90_modified planning target volume covering 90 % plotted recurrences with avoidance of proximal organs at risk, PTV-80_modified planning target volume covering 80 % plotted recurrences with avoidance of proximal organs at risk

ISSN: 1748-717X