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Table 1 Patient characteristics

From: Suspected recurrence of brain metastases after focused high dose radiotherapy: can [18F]FET- PET overcome diagnostic uncertainties?

Lesion number Location Histology Previous RT TBR max TBR mean TAC TTP Months between RT and PET Final diagnosis Diagnostic determinant Follow up (months)
1 R parietal NSCLC SRS 1.5 1.4 n.a. n.a. 1.9 Radiation induced lesion Follow up 9.4
2 L insular Malignant melanoma SBT 3.4 2.3 Decreasing 12.5 2.1 Tumor Follow up 14.8
3 L insular Malignant melanoma SRS 3.4 2.3 Increasing 35 2.2 Tumor Histology 4.2
4 L parietooccipital NSCLC SBT 2.1 1.9 Decreasing 25 2.4 Tumor Histology 29.9
5 L occipital NSCLC SBT 2.8 2.1 Increasing 35 2.5 Radiation induced lesion Follow up 6.7
6 L frontal Malignant melanoma SBT 4.1 2.5 Increasing 35 2.6 Tumor Follow up 4.6
7 L parietal CUP SRS 1.8 1.8 Increasing 35 3 Radiation induced lesion Follow up 4.9
8 L pontine Breast cancer SRS 1.5 1.3 n.a. n.a. 4.6 Radiation induced lesion Follow up 30.9
9 R temporal Malignant melanoma SRS 2.1 1.9 Increasing 17.5 4.7 Radiation induced lesion Follow up 16
10 L frontal Malignant melanoma SRS 2.0 1.9 Decreasing 17.5 4.7 Tumor Histology 16
11 L cerebellar Breast cancer SRS 1.7 1.2 Increasing 35 4.7 Radiation induced lesion Follow up 30.9
12 R parietal Malignant melanoma SRS 1.4 1.0 n.a. n.a. 4.8 Radiation induced lesion Follow up 6.8
13 R parietal NSCLC SRS 1.5 1.4 n.a. n.a. 5.3 Tumor Histology 9.4
14 L insular Malignant melanoma SBT 3.2 2.3 Decreasing 17.5 5.4 Radiation induced lesion Follow up 14.8
15 R temporal NSCLC SRS 1.5 1.3 n.a. n.a. 6 Radiation induced lesion Follow up 13.6
16 L occipital NSCLC SRS 2.8 2.1 Decreasing 12.5 6 Tumor Histology 13.6
17 L temporal Malignant melanoma SRS 2.9 2.1 Increasing 35 6 Radiation induced lesion Follow up 33.8
18** R frontal Malignant melanoma SRS 1.4 1.3 Increasing 35 8 Radiation induced lesion Follow up 42.5
19 R cerebellar Gastrointestinal cancer SRS 2.3 2.0 Decreasing 12.5 8.5 Tumor Histology 18
20 L frontal NSCLC SRS 1.9 1.8 Increasing 35 8.6 Radiation induced lesion Histology 35.1
21 R frontal NSCLC SRS 1.6 1.4 Increasing 35 8.7 Radiation induced lesion Histology 43.1
22 L frontal NSCLC SRS 1.2 1.0 n.a. n.a. 8.7 Radiation induced lesion Follow up 43.1
23 L frontal Malignant melanoma SRS 2.4 2.0 Decreasing 25 9.1 Tumor Histology 22.2
24 R frontal Gastrointestinal cancer SRS 2.0 1.9 Increasing 25 9.3 Radiation induced lesion Histology 17.1
25 R frontal NSCLC SRS 2.0 1.9 Decreasing 25 9.3 Radiation induced lesion Histology 23.8
26 R temporal NSCLC SRS 1.5 1.1 n.a. n.a. 9.4 Radiation induced lesion Follow up 13.6
27 L insular Malignant melanoma SBT 3.5 2.4 Decreasing 7.5 10.5 Radiation induced lesion Follow up 14.8
28 L parietal Malignant melanoma SBT 2.5 2.1 Decreasing 12.5 12.3 Tumor Histology 14.5
29 R temporal Malignant melanoma SRS 1.5 1.2 n.a. n.a. 14 Radiation induced lesion Follow up 16
30* L frontal Malignant melanoma SRS 3.5 2.3 Decreasing 7.5 14 Tumor Histology 16
31 L insular Malignant melanoma SBT 3.5 2.4 Decreasing 12.5 14.7 Radiation induced lesion Follow up 14.8
32 R occipital Breast cancer SRS 1.8 1.8 Increasing 35 15 Radiation induced lesion Follow up 79.2
33 R frontal Breast cancer SRS 2.0 1.9 Increasing 35 15 Radiation induced lesion Follow up 79.2
34 L cerebellar Breast cancer SRS 1.8 1.7 Increasing 35 15 Radiation induced lesion Follow up 79.2
35 L occipital NSCLC SRS 3.0 2.1 Decreasing 4 15.8 Tumor Histology 25.1
36 L frontal Malignant melanoma SRS 2.1 1.9 Increasing 35 18.2 Radiation induced lesion Follow up 24.1
37 R frontal NSCLC SRS 3.0 2.2 Decreasing 12.5 18.6 Tumor Follow up 23.8
38 R frontal Malignant melanoma SRS 3.5 2.2 Increasing 25 19.8 Tumor Follow up 42.5
39 R frontal Malignant melanoma SRS 2.2 2.0 Decreasing 4 19.8 Tumor Follow up 42.5
40 L cerebellar Breast cancer SRS 3.8 2.7 Increasing 35 19.9 Tumor Histology 30.9
41 L pontine Breast cancer SRS 4.3 2.8 Decreasing 25 19.9 Tumor Histology 30,9
42 L frontal Malignant melanoma SRS 2.0 1.9 Decreasing 17.5 20.3 Radiation induced lesion Follow up 24.1
43 L frontal Malignant melanoma SRS 2.4 2.0 Decreasing 25 20.8 Tumor Histology 22.2
44 R frontal NSCLC SRS 3.9 2.6 Decreasing 12.5 22.6 Tumor Follow up 23.8
45 R frontal Breast cancer SRS 1.5 1.4 Decreasing 25 22.9 Radiation induced lesion Follow up 33
46 L cerebellar Breast cancer SRS 2.4 2.0 Decreasing 17.5 22.9 Tumor Histology 33
47 R cerebellar NSCLC SRS 2.6 2.0 Decreasing 17.5 23.5 Radiation induced lesion Histology 33.6
48 R frontal Malignant melanoma SRS 1.4 1.3 Decreasing 4 28.4 Radiation induced lesion Follow up 42.5
49 L parietal NSCLC SRS 1.7 1.5 Increasing 35 42.2 Radiation induced lesion Follow up 51.5
50 R cerebellar Renal cell carcinoma SRS 2.9 2.1 Decreasing 17.5 90.3 Tumor Histology 99.1
  1. (*Fig. 1)
  2. (**Fig. 2)