Table 4 Multivariate analysis
From: Mucosal melanoma of the head and neck: a population-based study from Slovenia, 1985-2013
Prognostic factora | LC | LRC | DMFS | OS | ||||
|---|---|---|---|---|---|---|---|---|
HR (95 % CI) | p-value | HR (95 % CI) | p-value | HR (95 % CI) | p-value | HR (95 % CI) | p-value | |
Age (years) | ||||||||
<65 | NI | NI | 1.0 | 1.0 | ||||
>65 | 1.2 (0.40–3.4) | 0.793 | 0.89 (0.31–2.6) | 0.836 | ||||
Performance status (WHO) | ||||||||
0 | 1.0 | 0.523 | 1.0 | 0.473 | NI | 1.0 | 0.022 | |
1 | 0.73 (0.24–2.2) | 0.576 | 0.61 (0.23–1.6) | 0.315 | 1.2 (0.52–2.9) | 0.640 | ||
2+3+4 | 1.9 (0.31–12) | 0.483 | 1.4 (0.25–7.6) | 0.722 | 7.7 (1.7–34) | 0.008 | ||
Site | ||||||||
SN | 2.1 (0.52–8.7) | 0.298 | 2.1 (0.64–7.4) | 0.216 | NI | NI | ||
OC-OP | 1.0 | 1.0 | ||||||
Pigmented lesion | ||||||||
Yes | NI | NI | 1.0 | NI | ||||
No | 1.2 (0.40–3.4) | 0.779 | ||||||
Treatment modality | ||||||||
Surgery | 2.2 (0.42–12) | 0.355 | 4.7 (0.98–22) | 0.054 | NI | 1.0 (0.46–2.2) | 0.979 | |
RT | 11 (2.1–63) | 0.005 | 16 (3.0–80) | 0.001 | 2.0 (0.73–5.5) | 0.175 | ||
surgery+PORT | 1.0 | 0.005 | 1.0 | 0.002 | 1.0 | 0.303 | ||
Systemic therapy | ||||||||
Yes | NI | NI | 1.0 | 1.0 | ||||
No | 2.6 (0.62–11) | 0.193 | 3.1 (0.92–10) | 0.068 | ||||