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Table 3 Univariate analysis

From: Mucosal melanoma of the head and neck: a population-based study from Slovenia, 1985-2013

Prognostic factor Outcome (p-value )*
LC LRC DMFS DSS OS
Age (years)
  < 65 vs. >65 0.188 0.135 0.083 0.074 0.036
Sex
 Male vs. Female 0.674 0.241 0.425 0.276 0.189
Performance status (WHO)
 0 vs. 1 vs. 2 + 3 + 4 0.034 0.095 0.860 <0.001 <0.001
Site
 SN vs. OC-OP 0.125 0.056 0.291 0.581 0.768
Pigmented lesion
 Yes vs. No 0.888 0.953 0.157 0.329 0.246
T-stage
 T3 vs. T4A/B 0.752 0.931 0.643 0.291 0.226
N-stage
 N0 vs. N+ 0.612 0.650 0.892 0.741 0.742
TNM-stage
 III vs. IVA/B 0.595 0.708 0.807 0.382 0.315
Year of first treatment
 1985–2007 vs. 2008–2013 0.926 0.286 0.860 0.777 0.916
Treatment modality
 Surgery vs. RT vs. surgery + PORT <0.001 <0.001 0.796 0.111 0.074
Systemic therapy
 Yes vs. No 0.858 0.376 0.036 0.022 0.011
Failure of local control
 Yes vs. No NA NA 0.994 0.802 0.905
Failure of regional control
 Yes vs. No 0.720 NA 0.498 0.636 0.472
Failure of distant control
 Yes vs. No 0.741 0.434 NA 0.088 0.234
  1. *Regional control was not used in Kaplan-Meier calculations due to low number of events (N = 8).
  2. LC Local control, RC Regional control, LRC Locoregional control, DMFS Distant metastasis-free survival; DSS Disease-specific survival, OS Overall survival, WHO World Health Organization, SN Sinonasal, OC-OP Oral cavity/oropharynx, RT Radiotherapy, PORT Postoperative radiotherapy, NA Not applicable