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Table 3 Univariate analysis

From: Mucosal melanoma of the head and neck: a population-based study from Slovenia, 1985-2013

Prognostic factor

Outcome (p-value )*

LC

LRC

DMFS

DSS

OS

Age (years)

  < 65 vs. >65

0.188

0.135

0.083

0.074

0.036

Sex

 Male vs. Female

0.674

0.241

0.425

0.276

0.189

Performance status (WHO)

 0 vs. 1 vs. 2 + 3 + 4

0.034

0.095

0.860

<0.001

<0.001

Site

 SN vs. OC-OP

0.125

0.056

0.291

0.581

0.768

Pigmented lesion

 Yes vs. No

0.888

0.953

0.157

0.329

0.246

T-stage

 T3 vs. T4A/B

0.752

0.931

0.643

0.291

0.226

N-stage

 N0 vs. N+

0.612

0.650

0.892

0.741

0.742

TNM-stage

 III vs. IVA/B

0.595

0.708

0.807

0.382

0.315

Year of first treatment

 1985–2007 vs. 2008–2013

0.926

0.286

0.860

0.777

0.916

Treatment modality

 Surgery vs. RT vs. surgery + PORT

<0.001

<0.001

0.796

0.111

0.074

Systemic therapy

 Yes vs. No

0.858

0.376

0.036

0.022

0.011

Failure of local control

 Yes vs. No

NA

NA

0.994

0.802

0.905

Failure of regional control

 Yes vs. No

0.720

NA

0.498

0.636

0.472

Failure of distant control

 Yes vs. No

0.741

0.434

NA

0.088

0.234

  1. *Regional control was not used in Kaplan-Meier calculations due to low number of events (N = 8).
  2. LC Local control, RC Regional control, LRC Locoregional control, DMFS Distant metastasis-free survival; DSS Disease-specific survival, OS Overall survival, WHO World Health Organization, SN Sinonasal, OC-OP Oral cavity/oropharynx, RT Radiotherapy, PORT Postoperative radiotherapy, NA Not applicable
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Radiation Oncology

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