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Table 1 Epidemiological and clinical parameters of 61 patients with MMHN diagnosed in Slovenia, 1985–2013

From: Mucosal melanoma of the head and neck: a population-based study from Slovenia, 1985-2013

Characteristic All cases Sinonasal tract Oral cavity & oropharynx p-value 
N = 61 (%) N = 44 (%) N = 16 (%)
Age at diagnosis (years)
 Median 75.5 77.0 68.2 0.059
 Range 25.9–91.8 40.0–91.8 25.9–87.3  
Sex
 Male 32 (53) 20 (46) 11 (69) 0.110
 Female 29 (48) 24 (55) 5 (31)  
PS WHO
 Grade 0 29 (48) 18 (41) 10 (63) 0.276
 Grade 1 23 (38) 18 (41) 5 (31)  
 Grade >1 9 (15) 8 (18) 1 (6.3)  
Duration of symptoms (months)
 Median 2.0 2.0 1.0 0.554
 Range 0.0–12.0 0.0–12.0 0.0–12.0  
Tumor pigmentation
 Yes 36 (59) 23 (52) 13 (81) 0.165
 No 13 (21) 11 (25) 2 (13)  
 Unknown 12 (20) 10 (237) 1 (6.3)  
Overall stage
 1 48 (79) 38 (86) 9 (56) 0.029
 2 10 (16) 4 (9.1) 6 (38)  
 3 3 (4.9) 2 (4.5) 1 (6.3)  
TNM stage
 III 21 (34) 16 (36) 4 (25) 0.203
 IVA 30 (49) 19 (43) 11 (69)  
 IVB 7 (12) 7 (16) 0 (0.0)  
 IVC 3 (4.9) 2 (4.5) 1 (6.3)  
Treatment intent
 Curative 48 (79) 33 (75) 14 (88) 0.299
 Palliative 13 (21) 11 (25) 2 (13)  
Surgery
 No 22 (36) 20 (46) 2 (13) 0.019
 Yes 39 (64) 24 (55) 14 (88)  
  Open surgery 24 (62) 10 (42) 13 (93) 0.002
  Endoscopic surgery 15 (39) 14 (58) 1 (7.1)  
Radiotherapy
 No 28 (46) 21 (48) 7 (44) 0.785
 Yes 33 (54) 23 (52) 9 (56)  
  Definitive 11 (33) 9 (39) 2 (22) 0.066
  Postoperative 16 (49) 8 (35) 7 (78)  
  Palliative 6 (18) 6 (26) 0 (0.0)  
Systemic therapy
 Yes 13 (21) 10 (23) 3 (19) 0.741
 No 48 (79) 34 (77) 13 (81)  
2-year overall survivala 43 (30–55) 40 (26–55) 54 (29–79) 0.548
5-year overall survivala 18 (7.8–29) 20 (7.4–32) 15 (0.0–35) 0.548
  1. a% (95 % confidence interval). N Number of patients