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Table 1 Patient characteristics

From: Reduced volume SIB-IMRT/IGRT to head and neck cancer in elderly and frail patients: outcome and toxicity

Characteristics

All patients

 

Number

Percentage

Age at diagnosis, median (range) [years]

69.2 (49-87)

 

 Sex

  male

24

88.9

  female

3

11.1

 Karnofsky performance status

  100-90

3

11.1

  80-70

17

63.0

  60-50

6

22.2

  40-30

1

3,7

BMI, median (range) [kg/m2]

22.7 (17.8-35.9)

Comorbidities, median (range)

4 (1-15)

 

  Cardiac and Vascular-diseaseb

15

55.6

  Lung-diseasec

8

29.6

  Liver-disease

4

14.8

  Diabetes

2

7.4

  Alcohol abuse

15

55.6

  Dementia

5

18.5

  Cachexiad

8

29.6

 Charlson comorbidity Index

  2-4

13

48.1

  5-8

10

37.0

  9-12

4

14.8

 Laboratory findings

  decreased Cholin Esterasea

11

 

  increased CRP (>1.0 g/dl)

12

44.4

 UICC Stage

  IVa

14

51.8

  IVb

4

14.8

  IVc

9

33.3

 Histology

  Squamous cell carcinoma

25

92.6

  Adenocarcinoma

1

3.7

  Mucoepidermoid carcinoma

1

3.7

 Reason for non-radical treatmentb

  Tumor size not suitable for radical treatment

5

18.5

  Metastatic disease

9

33.3

  Age and/or severe comorbidity

21

77.8

  Re-Radiotherapy

1

3.7

  1. a 14 patients analysed
  2. b Including coronary heart disease, myocardial infarction, arrhythmia, congestive heart failure
  3. c Including emphysema, COPD, high frequency of pneumonia
  4. d Defined as progressive, unwanted weight-loss