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Table 1 Objective function parameters for all volumes v

From: Worst case optimization for interfractional motion mitigation in carbon ion therapy of pancreatic cancer

v d O [Gy(RBE)] d U [Gy(RBE)] p v
GTV 54 54 Individual
Spinal Cord 10 200
Kidneys 5 250
Stomach 15 15
Intestine 15 15
Liver 15 15
Normal Tissue 15 5
  1. d O/U hresholds for over- and under-dose, respectively. Note that the dose values have to be converted into thresholds in over- and under-effect according to the LQM for effect-based optimization. For the target volumes, the penalties p v were adjusted individually for all four treatment planning strategies but kept the same for OARs