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Table 2 Quality of Life Scores among Nasopharyngeal Carcinoma Survivors by Time since Radiotherapy (n = 44)

From: Long-term disease-specific and cognitive quality of life after intensity-modulated radiation therapy: a cross-sectional survey of nasopharyngeal carcinoma survivors

  

Time since End of Radiotherapy Treatment

Mean ± Standard deviation

 

Item

Total (n = 44)

Cohort 1

≤2.5 years

(n = 11)

Cohort 2

>2.5–6 years

(n = 13)

Cohort 3

>6–10 years

(n = 9)

Cohort 4

>10 years

(n = 11)

ANOVA p-value

FACT-NP Total (0–172)a

119.3 ± 24.7

98.8 ± 19.9

133.7 ± 18.9

128.5 ± 31.0

115.3 ± 14.4

0.002

 NPC Subscore (NPCS) (0–64)

39.7 ± 11.1

34.9 ± 10.5

46.5 ± 9.2

41.9 ± 13.4

34.7 ± 7.5

0.017

 FACT-G Component (0–108)

79.6 ± 17.0

63.9 ± 15.9

87.2 ± 11.1

86.6 ± 19.1

80.6 ± 12.7

0.002

  Functional Well-being (0–28)

19.0 ± 6.0

13.1 ± 4.3

20.1 ± 4.6

22.3 ± 7.3

21.0 ± 3.6

<0.001

  Emotional Well-being (0–24)

18.3 ± 4.2

14.5 ± 4.0

20.5 ± 2.5

19.3 ± 4.1

18.7 ± 4.2

0.003

  Social Well-being (0–28)

21.2 ± 6.0

18.1 ± 6.4

23.8 ± 3.7

23.0 ± 5.5

19.9 ± 7.2

0.08

  Physical Well-being (0–28)

21.0 ± 5.7

18.2 ± 7.1

22.8 ± 5.0

21.9 ± 5.9

21.0 ± 4.4

0.25

FACT-Cog Total (0–132)

98.9 ± 23.4

88.1 ± 22.9

113.2 ± 18.8

103.9 ± 20.9

88.9 ± 22.9

0.02

 Perceived Cognitive Abilities (0–28)

19.5 ± 5.6

15.8 ± 5.3

23.0 ± 4.9

20.8 ± 6.2

18.2 ± 3.5

0.01

 Perceived Cognitive Impairments (0–72)

54.6 ± 13.7

50.8 ± 14.1

62.3 ± 10.0

56.7 ± 10.4

47.8 ± 15.8

0.04

 Impact on Quality of Life (0–16)

11.3 ± 4.5

9.0 ± 5.2

13.5 ± 3.9

12.2 ± 4.5

10.4 ± 3.2

0.07

 Comments from Others (0–16)

13.4 ± 3.2

12.5 ± 3.9

14.4 ± 3.2

14.2 ± 1.6

12.5 ± 3.3

0.32

  1. Results of one-way ANOVA for measuring overall differences in FACT-NP and its subscales, as well as FACT-Cog and its subscales, are shown among the cohorts. FACT-NP is comprised of the NPC-specific score (NPCS) plus the general QoL (FACT-G) score. FACT-G includes four subdomains that measure functional, emotional, social and physical well-being. FACT-Cog measures cognitive QoL and is comprised of four subdomains that measure perceived cognitive abilities, perceived cognitive impairments, impact on QoL and comments from others. Significant values (P < 0.05) are in bold
  2. aNumbers in parenthesis indicate the range of possible scores