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Table 2 Quality of Life Scores among Nasopharyngeal Carcinoma Survivors by Time since Radiotherapy (n = 44)

From: Long-term disease-specific and cognitive quality of life after intensity-modulated radiation therapy: a cross-sectional survey of nasopharyngeal carcinoma survivors

   Time since End of Radiotherapy Treatment
Mean ± Standard deviation
 
Item Total (n = 44) Cohort 1
≤2.5 years
(n = 11)
Cohort 2
>2.5–6 years
(n = 13)
Cohort 3
>6–10 years
(n = 9)
Cohort 4
>10 years
(n = 11)
ANOVA p-value
FACT-NP Total (0–172)a 119.3 ± 24.7 98.8 ± 19.9 133.7 ± 18.9 128.5 ± 31.0 115.3 ± 14.4 0.002
 NPC Subscore (NPCS) (0–64) 39.7 ± 11.1 34.9 ± 10.5 46.5 ± 9.2 41.9 ± 13.4 34.7 ± 7.5 0.017
 FACT-G Component (0–108) 79.6 ± 17.0 63.9 ± 15.9 87.2 ± 11.1 86.6 ± 19.1 80.6 ± 12.7 0.002
  Functional Well-being (0–28) 19.0 ± 6.0 13.1 ± 4.3 20.1 ± 4.6 22.3 ± 7.3 21.0 ± 3.6 <0.001
  Emotional Well-being (0–24) 18.3 ± 4.2 14.5 ± 4.0 20.5 ± 2.5 19.3 ± 4.1 18.7 ± 4.2 0.003
  Social Well-being (0–28) 21.2 ± 6.0 18.1 ± 6.4 23.8 ± 3.7 23.0 ± 5.5 19.9 ± 7.2 0.08
  Physical Well-being (0–28) 21.0 ± 5.7 18.2 ± 7.1 22.8 ± 5.0 21.9 ± 5.9 21.0 ± 4.4 0.25
FACT-Cog Total (0–132) 98.9 ± 23.4 88.1 ± 22.9 113.2 ± 18.8 103.9 ± 20.9 88.9 ± 22.9 0.02
 Perceived Cognitive Abilities (0–28) 19.5 ± 5.6 15.8 ± 5.3 23.0 ± 4.9 20.8 ± 6.2 18.2 ± 3.5 0.01
 Perceived Cognitive Impairments (0–72) 54.6 ± 13.7 50.8 ± 14.1 62.3 ± 10.0 56.7 ± 10.4 47.8 ± 15.8 0.04
 Impact on Quality of Life (0–16) 11.3 ± 4.5 9.0 ± 5.2 13.5 ± 3.9 12.2 ± 4.5 10.4 ± 3.2 0.07
 Comments from Others (0–16) 13.4 ± 3.2 12.5 ± 3.9 14.4 ± 3.2 14.2 ± 1.6 12.5 ± 3.3 0.32
  1. Results of one-way ANOVA for measuring overall differences in FACT-NP and its subscales, as well as FACT-Cog and its subscales, are shown among the cohorts. FACT-NP is comprised of the NPC-specific score (NPCS) plus the general QoL (FACT-G) score. FACT-G includes four subdomains that measure functional, emotional, social and physical well-being. FACT-Cog measures cognitive QoL and is comprised of four subdomains that measure perceived cognitive abilities, perceived cognitive impairments, impact on QoL and comments from others. Significant values (P < 0.05) are in bold
  2. aNumbers in parenthesis indicate the range of possible scores