Skip to main content

Table 1 Characteristics of included studies

From: Involved field radiotherapy (IFRT) versus elective nodal irradiation (ENI) for locally advanced non-small cell lung cancer: a meta-analysis of incidence of elective nodal failure (ENF)

Study Years of inclusion Study arms Patients (n) RT dose Chemotherapy Follow-up time (months) Number of ENF
RCTs
 Yuan 2007 1997–2001 IFRT 100 68-74Gy Concurrent 27 (median) 7
   ENI 100 60-64Gy   27 (median) 4
 Yang 2007 2002–2004 IFRT 29 66-74Gy Sequential Till December 2005 3
   ENI 26 56-70Gy   Till December 2005 1
 Chen 2013 2002–2011 IFRT 45 38-74Gy Concurrent 14.1 (median) 2
   ENI 54 32-70Gy   14.1 (median) 4
Cohort studies
 Fernandes 2010 2003–2008 IFRT 48 60-84Gy Concurrent or sequential 13.5 (median) 6
   ENI 60 54-72Gy   17 (median) 7
 Kolodziejczyk 2012 2008–2009 IFRT 35 58.8Gy Sequential 32 (median) 1
   ENI 17 58.8Gy   32 (median) 0
 Topkan 2015 2007–2012 IFRT 143 60–66Gy Concurrent 23.3 (median) 3
   ENI 844 60–66Gy   23.3 (median) 21
  1. Note: IFRT involved field radiotherapy, ENI elective nodal irradiation, ENF elective nodal failure, Gy gray