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Table 1 Characteristics of included studies

From: Involved field radiotherapy (IFRT) versus elective nodal irradiation (ENI) for locally advanced non-small cell lung cancer: a meta-analysis of incidence of elective nodal failure (ENF)

Study

Years of inclusion

Study arms

Patients (n)

RT dose

Chemotherapy

Follow-up time (months)

Number of ENF

RCTs

 Yuan 2007

1997–2001

IFRT

100

68-74Gy

Concurrent

27 (median)

7

  

ENI

100

60-64Gy

 

27 (median)

4

 Yang 2007

2002–2004

IFRT

29

66-74Gy

Sequential

Till December 2005

3

  

ENI

26

56-70Gy

 

Till December 2005

1

 Chen 2013

2002–2011

IFRT

45

38-74Gy

Concurrent

14.1 (median)

2

  

ENI

54

32-70Gy

 

14.1 (median)

4

Cohort studies

 Fernandes 2010

2003–2008

IFRT

48

60-84Gy

Concurrent or sequential

13.5 (median)

6

  

ENI

60

54-72Gy

 

17 (median)

7

 Kolodziejczyk 2012

2008–2009

IFRT

35

58.8Gy

Sequential

32 (median)

1

  

ENI

17

58.8Gy

 

32 (median)

0

 Topkan 2015

2007–2012

IFRT

143

60–66Gy

Concurrent

23.3 (median)

3

  

ENI

844

60–66Gy

 

23.3 (median)

21

  1. Note: IFRT involved field radiotherapy, ENI elective nodal irradiation, ENF elective nodal failure, Gy gray