Prognostic value of phosphorylated Raf kinase inhibitory protein at serine 153 and its predictive effect on the clinical response to radiotherapy in nasopharyngeal carcinoma

Table 1 The correlation of p-Ser153 RKIP expression with clinical characteristical factors

Characteristic	Total		p-Ser153 RKIP expression
	(n = 733)		Negative		Positive		P value
	No.	%	No.	%	No.	%	P value
Age, y(median)
≤46	362	49.39	164	45.3	198	54.7	0.468
>46	371	50.61	178	48.0	193	52.0
Sex
Male	394	53.75	168	42.6	226	57.4	0.019
Female	339	46.25	174	51.3	165	487
N classification
N₀₊₁	377	51.43	174	46.2	203	53.8	0.778
N₂₊₃	356	48.57	168	47.2	188	52.8
T classification
T₁₊₂	438	59.75	188	42.9	250	57.1	0.014
T₃₊₄	295	40.25	154	52.2	141	47.8
TNM classification
I + II	335	57.57	160	47.8	175	52.2	0.583
III + IVa + b	398	42.43	182	45.7	216	54.3
Pathologic classification
Type I	10	1.36	4	40	6	60	0.116
Type II	84	11.32	48	57.1	36	42.9
Type III	639	87.31	290	45.4	349	54.6
Survival status
Yes	415	56.62	130	31.3	285	68.7	<0.001
No	318	43.38	212	66.7	106	33.3
Local-regional relapse
Yes	155	21.15	92	59.4	63	40.6	0.001
No	578	78.85	250	43.3	328	56.7
Post-treatment progression
Yes	324	44.20	197	60.8	127	39.2	<0.001
No	409	56.80	145	35.5	264	64.5
Post-treatment distant metastasis
Yes	224	30.56	125	55.8	99	44.2	0.001
No	509	69.44	217	42.6	292	57.4

ISSN: 1748-717X