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Table 2 Estimated changes in SF-36 scores from the start of RT, the end of RT and 1 year after RT compared to baseline are listed on the left. The impact of the covariates on the scores is listed on the right

From: Prospective assessment of the quality of life before, during and after image guided intensity modulated radiotherapy for prostate cancer

Scale

Time

Covariates

 

Mean change from baseline (95 % CI)

Mean change (95 % CI)

Start RT

End RT

1 year after RT

Age

Comorb.

Smok.

ADT

Urinary bother

GI bother

Sexual bother

Physical functioning

−0.7 (−3.6;2.2)

−3.8 (−6.7; −0.9)

−3.6 (−6.5; −0.7)

−0.2 (−0.7;0.3)

−7.0 (−13.8; −0.3)

−0.5 (−7.8;6.8)

−2.1 (−7.7;3.5)

−0.6 (−1.1; −0.1)

0.1 (−0.6;0.7)

0.2 (−0.2;0.6)

p = 0.638

p = 0.010*

p = 0.015*

p = 0.387

p = 0.041*

p = 0.897

p = 0.464

p = 0.014*

p = 0.865

p = 0.357

Role physical

13.3 (4.0;22.6)

1.5 (−7.9;11.0)

11.4 (2.0;20.8)

−0.2 (−1.4;1.0)

−7.2 (−22.8;8.4)

−1.2 (−18.1;15.8)

−6.8 (−24.5;10.9)

−3.3 (−4.8; −1.9)

−1.0 (−2.9;1.0)

0.1 (−1.1;1.3)

p = 0.005*

p = 0.754

p = 0.018*

p = 0.741

p = 0.362

p = 0.890

p = 0.450

p < 0.001*

p = 0.320

p = 0.873

Bodily pain

11.9 (6.1;17.7)

0.0 (−5.9;5.8)

11.4 (5.5;17.3)

−0.2 (−0.8;0.4)

0.8 (−7.4;9.1)

−2.6 (−11.6;6.3)

2.1 (−8.7;12.9)

−1.4 (−2.3; −0.5)

−2.0 (−3.2; −0.9)

0.0 (−0.7;0.7)

p < 0.001*

p = 0.990

p < 0.001*

p = 0.558

p = 0.840

p = 0.562

p = 0.698

p = 0.002*

p = 0.001*

p = 0.987

General health

0.6 (−2.5;3.8)

−2.0 (−5.2;1.2)

−3.6 (−6.8; −0.3)

0.5 (0.0;1.1)

−8.4 (−15.8; −1.0)

0.4 (−7.6;8.3)

−5.7 (−11.9;0.6)

−0.6 (−1.1;0.0)

−1.0 (−1.7; −0.3)

0.1 (−0.3;0.5)

p = 0.687

p = 0.222

p = 0.031*

p = 0.071

p = 0.026*

p = 0.931

p = 0.075

p = 0.040*

p = 0.004*

p = 0.588

PCS

2.1 (0.5;3.7)

−1.1 (−2.7;0.5)

0.7 (−0.9;2.3)

−0.1 (−0.3;0.2)

−2.0 (−5.3;1.3)

0.5 (−3.0;4.1)

−1.7 (−4.7;1.3)

−0.5 (−0.8; −0.3)

−0.4 (−0.7;0.0)

0.2 (0.0;0.4)

p = 0.008*

p = 0.181

p = 0.392

p = 0.584

p = 0.225

p = 0.763

p = 0.270

p < 0.001*

p = 0.032*

p = 0.113

Vitality

2.9 (−1.0;6.9)

−4.4 (−8.4; −0.4)

1.3 (−2.7;5.3)

0.6 (−0.1;1.3)

−7.3 (−16.5;1.8)

−5.5 (−15.4;4.4)

0.1 (−7.6;7.8)

−1.1 (−1.7; −0.4)

−1.0 (−1.8; −0.1)

−0.2 (−0.8;0.3)

p = 0.144

p = 0.030*

p = 0.517

p = 0.087

p = 0.113

p = 0.271

p = 0.979

p = 0.001*

p = 0.028*

p = 0.378

Social functioning

3.0 (−0.9;6.9)

−2.3 (−6.3;1.7)

3.7 (−0.3;7.7)

0.4 (−0.2;0.9)

−4.8 (−11.6;2.1)

2.6 (−4.9;10.0)

4.9 (−2.8;12.6)

−0.5 (−1.1;0.1)

−1.3 (−2.1; −0.5)

−0.3 (−0.8;0.2)

p = 0.134

p = 0.261

p = 0.068

p = 0.171

p = 0.170

p = 0.495

p = 0.210

p = 0.132

p = 0.003*

p = 0.240

Role emotional

4.6 (−3.2;12.5)

−0.1 (−8.1;7.8)

2.1 (−5.8;10.1)

0.3 (−0.8;1.3)

−6.6 (−20.4;7.3)

−4.4 (−19.4;10.6)

−2.2 (−17.3;12.9)

−1.4 (−2.7; −0.2)

−0.9 (−2.6; −0.2)

−0.8 (−1.8;0.2)

p = 0.248

p = 0.972

p = 0.598

p = 0.597

p = 0.348

p = 0.565

p = 0.773

p = 0.028*

p = 0.266

p = 0.099

Mental health

5.1 (1.5;8.8)

2.0 (−1.7;5.7)

6.3 (2.6;10.0)

0.3 (−0.2;0.8)

−5.7 (−12.7;1.3)

−7.1 (−14.7;0.4)

2.8 (−4.4;9.9)

−0.8 (−1.4; −0.2)

−0.6 (−1.4;0.2)

−0.3 (−0.8;0.1)

p = 0.006*

p = 0.282

p = 0.001*

p = 0.242

p = 0.107

p = 0.065

p = 0.445

p = 0.014*

p = 0.129

p = 0.148

MCS

1.7 (−0.3;3.8)

0.1 (−2.0;2.1)

2.1 (0.0;4.1)

0.3 (0.0;0.5)

−2.8 (−6.6;1.0)

−2.6 (−6.7;1.5)

1.4 (−2.5;5.4)

−0.3 (−0.7;0.0)

−0.4 (−0.9;0.0)

−0.3 (−0.6;0.0)

p = 0.091

p = 0.931

p = 0.047*

p = 0.072

p = 0.149

p = 0.208

p = 0.473

p = 0.052

p = 0.055

p = 0.026*

  1. RT Radiotherapy
  2. PCS Physical Component Scale
  3. MCS Mental Component Scale
  4. *Statistically significant