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Table 2 Estimated changes in SF-36 scores from the start of RT, the end of RT and 1 year after RT compared to baseline are listed on the left. The impact of the covariates on the scores is listed on the right

From: Prospective assessment of the quality of life before, during and after image guided intensity modulated radiotherapy for prostate cancer

Scale Time Covariates
  Mean change from baseline (95 % CI) Mean change (95 % CI)
Start RT End RT 1 year after RT Age Comorb. Smok. ADT Urinary bother GI bother Sexual bother
Physical functioning −0.7 (−3.6;2.2) −3.8 (−6.7; −0.9) −3.6 (−6.5; −0.7) −0.2 (−0.7;0.3) −7.0 (−13.8; −0.3) −0.5 (−7.8;6.8) −2.1 (−7.7;3.5) −0.6 (−1.1; −0.1) 0.1 (−0.6;0.7) 0.2 (−0.2;0.6)
p = 0.638 p = 0.010* p = 0.015* p = 0.387 p = 0.041* p = 0.897 p = 0.464 p = 0.014* p = 0.865 p = 0.357
Role physical 13.3 (4.0;22.6) 1.5 (−7.9;11.0) 11.4 (2.0;20.8) −0.2 (−1.4;1.0) −7.2 (−22.8;8.4) −1.2 (−18.1;15.8) −6.8 (−24.5;10.9) −3.3 (−4.8; −1.9) −1.0 (−2.9;1.0) 0.1 (−1.1;1.3)
p = 0.005* p = 0.754 p = 0.018* p = 0.741 p = 0.362 p = 0.890 p = 0.450 p < 0.001* p = 0.320 p = 0.873
Bodily pain 11.9 (6.1;17.7) 0.0 (−5.9;5.8) 11.4 (5.5;17.3) −0.2 (−0.8;0.4) 0.8 (−7.4;9.1) −2.6 (−11.6;6.3) 2.1 (−8.7;12.9) −1.4 (−2.3; −0.5) −2.0 (−3.2; −0.9) 0.0 (−0.7;0.7)
p < 0.001* p = 0.990 p < 0.001* p = 0.558 p = 0.840 p = 0.562 p = 0.698 p = 0.002* p = 0.001* p = 0.987
General health 0.6 (−2.5;3.8) −2.0 (−5.2;1.2) −3.6 (−6.8; −0.3) 0.5 (0.0;1.1) −8.4 (−15.8; −1.0) 0.4 (−7.6;8.3) −5.7 (−11.9;0.6) −0.6 (−1.1;0.0) −1.0 (−1.7; −0.3) 0.1 (−0.3;0.5)
p = 0.687 p = 0.222 p = 0.031* p = 0.071 p = 0.026* p = 0.931 p = 0.075 p = 0.040* p = 0.004* p = 0.588
PCS 2.1 (0.5;3.7) −1.1 (−2.7;0.5) 0.7 (−0.9;2.3) −0.1 (−0.3;0.2) −2.0 (−5.3;1.3) 0.5 (−3.0;4.1) −1.7 (−4.7;1.3) −0.5 (−0.8; −0.3) −0.4 (−0.7;0.0) 0.2 (0.0;0.4)
p = 0.008* p = 0.181 p = 0.392 p = 0.584 p = 0.225 p = 0.763 p = 0.270 p < 0.001* p = 0.032* p = 0.113
Vitality 2.9 (−1.0;6.9) −4.4 (−8.4; −0.4) 1.3 (−2.7;5.3) 0.6 (−0.1;1.3) −7.3 (−16.5;1.8) −5.5 (−15.4;4.4) 0.1 (−7.6;7.8) −1.1 (−1.7; −0.4) −1.0 (−1.8; −0.1) −0.2 (−0.8;0.3)
p = 0.144 p = 0.030* p = 0.517 p = 0.087 p = 0.113 p = 0.271 p = 0.979 p = 0.001* p = 0.028* p = 0.378
Social functioning 3.0 (−0.9;6.9) −2.3 (−6.3;1.7) 3.7 (−0.3;7.7) 0.4 (−0.2;0.9) −4.8 (−11.6;2.1) 2.6 (−4.9;10.0) 4.9 (−2.8;12.6) −0.5 (−1.1;0.1) −1.3 (−2.1; −0.5) −0.3 (−0.8;0.2)
p = 0.134 p = 0.261 p = 0.068 p = 0.171 p = 0.170 p = 0.495 p = 0.210 p = 0.132 p = 0.003* p = 0.240
Role emotional 4.6 (−3.2;12.5) −0.1 (−8.1;7.8) 2.1 (−5.8;10.1) 0.3 (−0.8;1.3) −6.6 (−20.4;7.3) −4.4 (−19.4;10.6) −2.2 (−17.3;12.9) −1.4 (−2.7; −0.2) −0.9 (−2.6; −0.2) −0.8 (−1.8;0.2)
p = 0.248 p = 0.972 p = 0.598 p = 0.597 p = 0.348 p = 0.565 p = 0.773 p = 0.028* p = 0.266 p = 0.099
Mental health 5.1 (1.5;8.8) 2.0 (−1.7;5.7) 6.3 (2.6;10.0) 0.3 (−0.2;0.8) −5.7 (−12.7;1.3) −7.1 (−14.7;0.4) 2.8 (−4.4;9.9) −0.8 (−1.4; −0.2) −0.6 (−1.4;0.2) −0.3 (−0.8;0.1)
p = 0.006* p = 0.282 p = 0.001* p = 0.242 p = 0.107 p = 0.065 p = 0.445 p = 0.014* p = 0.129 p = 0.148
MCS 1.7 (−0.3;3.8) 0.1 (−2.0;2.1) 2.1 (0.0;4.1) 0.3 (0.0;0.5) −2.8 (−6.6;1.0) −2.6 (−6.7;1.5) 1.4 (−2.5;5.4) −0.3 (−0.7;0.0) −0.4 (−0.9;0.0) −0.3 (−0.6;0.0)
p = 0.091 p = 0.931 p = 0.047* p = 0.072 p = 0.149 p = 0.208 p = 0.473 p = 0.052 p = 0.055 p = 0.026*
  1. RT Radiotherapy
  2. PCS Physical Component Scale
  3. MCS Mental Component Scale
  4. *Statistically significant