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Table 2 Patient characteristics stratified by fractionation regimen

From: Impact of hypofractionation and tangential beam IMRT on the acute skin reaction in adjuvant breast cancer radiotherapy

Characteristic

Total

Fractionation regimen

p value

CF

HF

n

%

n

%

n

%

Country of origin

 Middle East

154

57.9

89

61.4

65

53.7

0.62

 Africa

60

22.6

31

21.4

29

24.0

 Asia

41

15.4

20

13.8

21

17.4

 Europe/U.S.A.

11

4.1

5

3.4

6

5.0

Age at diagnosis (years)

 Mean

49

 

49

 

49

 

0.85

 Standard Deviation

10

 

9

 

10

 

 ≤40

53

19.9

29

20.0

24

19.8

0.99

 41–50

103

38.7

55

37.9

48

39.7

 51–60

84

31.6

47

32.4

37

30.6

 >60

26

9.8

14

9.7

12

9.9

Laterality

 Left breast

63

48.5

35

50.7

28

45.9

0.58

 Right breast

67

51.5

34

49.3

33

54.1

 Left chest wall

76

55.9

42

55.3

34

56.7

0.87

 Right chest wall

60

44.1

34

44.7

26

43.3

Breast volume (ml)

 Median

1132

 

1000

 

1235

 

0.01

 Minimum

285

 

432

 

285

 

 Maximum

3613

 

2929

 

3613

 

Chest wall volume (ml)

 Median

715

 

695

 

776

 

0.02

 Minimum

110

 

110

 

230

 

 Maximum

2521

 

2521

 

1715

 

BMI

 Median

30.6

 

29.9

 

31.4

 

0.16

 Minimum

15.4

 

15.4

 

15.7

 

 Maximum

67.3

 

66.4

 

67.3

 

 <25

44

16.6

19

15.8

25

17.2

0.06

 25.0–29.9

73

27.5

25

20.8

48

33.1

 30.0–34.9

80

30.2

46

38.3

34

23.4

 35.0–39.9

46

17.4

19

15.8

27

18.6

 ≥40.0

22

8.3

11

9.2

11

7.6

Menopausal status

 Pre-menopausal

134

50.4

68

46.9

66

54.5

0.21

 Post-menopausal

132

49.6

77

53.1

55

45.5

Histopathology

 Invasive ductal cancer

246

92.5

135

93.1

111

91.7

0.05

 Invasive lobular cancer

13

4.9

8

5.5

5

4.1

 DCIS

5

1.9

0

0

5

4.1

 Other

2

0.8

2

1.4

0

0

T classification

 pTis

6

2.3

0

0.0

6

5.0

0.11

 pT0

7

2.6

2

1.4

5

4.1

 pT1

91

34.2

50

34.5

41

33.9

 pT2

104

39.1

59

40.7

45

37.2

 pT3

29

10.9

16

11.0

13

10.7

 pT4

19

7.1

11

7.6

8

6.6

 Not reported

10

3.8

7

4.8

3

2.5

N classification

 pN0

96

36.1

48

33.1

48

39.7

0.19

 pN1

76

28.6

42

29.0

34

28.1

 pN2

56

21.1

28

19.3

28

23.1

 pN3

31

11.7

21

14.5

10

8.3

 Not reported

7

2.6

6

4.1

1

0.8

M classification

 M0

263

98.9

143

98.6

120

99.2

0.67

 M1

3

1.1

2

1.4

1

0.8

Grading

 G1

22

8.3

5

3.4

17

14.0

0.02

 G2

82

30.8

45

31.0

37

30.6

 G3

137

51.5

80

55.2

57

47.1

 Not reported

22

8.3

5

3.4

17

14.0

ER status

 Negative

65

24.4

36

24.8

29

24.0

0.28

 Positive

191

71.8

106

73.1

85

70.2

 Not reported

10

3.8

3

2.1

7

5.8

PR status

 Negative

15

5.6

7

4.8

8

6.6

0.76

 Positive

79

29.7

42

29.0

37

30.6

 Not reported

172

64.7

96

66.2

76

62.8

Her2/neu status

 Negative

18

6.8

7

4.8

11

9.1

0.39

 Positive

178

66.9

99

68.3

79

65.3

 Not reported

70

26.3

39

26.9

31

25.6