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Table 5 Univariate analysis: Impact on survival after re-RT

From: Re-irradiation for locoregionally recurrent tumors of the thorax: a single-institution, retrospective study

Variable

Number

Median

LPFS

P value

Median

OS

P value

Sex

     

 Male

15

12.9

0.86

31.4

0.12

 Female

6

12.4

 

43.0

 

Age, years

     

  ≥ 75

9

13.9

0.96

37.3

0.97

  < 75

12

10.9

 

31.4

 

Interval between end of initial RT and recurrence, months

     

  ≥ 24

11

13.8

0.66

31.4

0.48

  < 24

10

10.9

 

31.0

 

Interval between initial RT and re-RT, months

     

  ≥ 24

11

13.8

0.66

31.4

0.48

  < 24

10

10.9

 

31.0

 

Re-RT dose, Gy10

     

  ≥ 60

16

18.2

0.04

37.4

0.41

  < 60

5

6.8

 

22.1

 

PTV size, cc

     

  > 75

8

12.9

0.78

16.9

0.03

  ≤ 75

13

13.8

 

43.5

 

Pathology

     

 NSCLC

14

13.9

0.88

31.4

0.56

 SCLC

7

10.9

 

37.5

 

Location

     

 Proximal

15

2.8

0.62

22.1

0.99

 Peripheral

6

18.2

 

37.4

 

Further chemotherapy after re-RT

     

 Yes

5

  

37.4

0.57

 No

9

  

31.4

 
  1. RT radiotherapy, re-RT re-irradiation, NSCLC Non small cell lung cancer, SCLC Small cell lung cancer, PTV planning target volume; Bold values represent statistically significant factors