Fig. 2

SKY results of the CAL-33 cell lines. The yellow arrows point the common for all CAL-33 cell lines marker chromosomes. The additional chromosomal rearrangements in analyzed clones compared to the parental CAL-33 cells are marked with white arrows. Structural and numerical aberrations in the parental CAL-33 cell line (a) involve chromosomes 3, 7, 8, 9 16, 18, 20, X, and Y. Aberrations of subclone SP (b) include chromosomes 2, 3, 7, 8, 9, 11, 16, 18, 20, 21, X, and Y. Chromosomal aberrations of subclone RP (c) affect chromosomes 1, 3, 4, 5, 7, 8, 9, 14, 16, 18, 20, X, and Y