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Table 1 Patient, tumour and treatment characteristics

From: Local radiotherapy alone following neoadjuvant chemotherapy and surgery in combined clinical stage II and III breast cancer

Characteristic

Number (total = 172)

%

Age

Median (range)

49 (27, 86)

 

Age group

<50

92

53.5 %

 

> = 50

80

46.5 %

Laterality

Right

92

53.5 %

 

Left

80

46.5 %

Breast location

Outter quadrant

95

55.2 %

 

Inner and/or central

59

34.3 %

 

Unknown

18

10.5 %

Clinical TNM stagea

cT stage

0-2

52

30.2 %

 

3

91

52.9 %

 

4

29

16.9 %

cN stage

0

69

40.1 %

 

1

101

58.7 %

 

2

2

1.2 %

combined c stage

II

111

64.5 %

 

III

61

35.5 %

Inflammatory

No

153

89.0 %

 

Yes

19

11.0 %

Histology

Ductal carcinoma

138

80.2 %

 

Lobular carcinoma

18

10.5 %

 

Other

16

9.3 %

Grade

1

8

4.7 %

 

2

91

52.9 %

 

3

73

42.4 %

ER status

Negative

64

37.2 %

 

Positive

101

58.7 %

 

Unknown

7

4.1 %

HER2 status

Negative

81

47.1 %

 

Amplified

33

19.2 %

 

Unknown

58

33.7 %

NAC regimen

Anthracycline

97

56.4 %

 

Taxane

16

9.3 %

 

Both

54

31.4 %

 

Neither

5

2.9 %

Surgery type

Lumpectomy

90

52.3 %

 

Mastectomy

82

47.7 %

Axillary nodes

median (range)

12 (1, 28)

 
 

<9 nodes

39

16.7 %

Pathological TNM stagea

yp T stage

0-2

154

89.5 %

 

3

13

7.6 %

 

4

2

1.2 %

 

unknown

3

1.7 %

yp N stage

0

95

55.2 %

 

1

77

44.8 %

combined yp stage

pCR

29

16.9 %

 

I

30

17.4 %

 

II

104

60.5 %

 

III

9

5.2 %

>1 node positive

No

138

80.2 %

 

Yes

34

19.8 %

Trastuzumab use

No

146

84.9 %

 

Yes

26

15.1 %

Radiotherapy schedule

40/15

158

91.9 %

(Gray/# fractions)

50/25

11

6.4 %

 

other

3

1.7 %

  1. aTNM stage as per AJCC staging manual v7