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Fig. 2 | Radiation Oncology

Fig. 2

From: Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo

Fig. 2

ROS production by the TiOxNPs, PAA-TiOxNPs, and TiO2NPs under X-ray irradiation. a APF intensity indicating that hydroxyl radical production in the TiOxNPs and the PAA-TiOxNPs increased in a radiation dose-dependent manner, but that of the TiO2NPs did not. Irradiated radiation doses were 0, 5, 10, and 30 Gy. Data are shown as the mean ± SD from 5 independent experiments. b Production and scavenging of ROS by 1 mM vitamin C (Vit. C) or 1 mM glutathione (GSH). Histograms show mean ± SD calculated from 5 independent experiments. c Hydrogen peroxide production from the TiOxNPs under X-ray irradiation. d Detection of intracellular ROS production by FACS. Mean fluorescence values are shown in each figure

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Radiation Oncology

ISSN: 1748-717X

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