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Table 4 Volumes of standard and simulated PTVs on the basis of FET-PET

From: Relapse patterns after radiochemotherapy of glioblastoma with FET PET-guided boost irradiation and simulation to optimize radiation target volume

Pat. No. PTV-2 MRI
standard (ml)
PTV FET-1
+5 mm margin (ml)
PTV FET-1
+7 mm margin (ml)
PTV FET-1
+10 mm margin (ml)
1 245 122 147 214
2 164 98 118 163
3 117 92 112 143
4 248 125 150 194
5 161 101 114 146
6 256 182 213 286
7 224 106 126 166
8 348 216 253 308
9 209 161 187 259
10 160 138 160 216
11 364 233 263 304
12 386 265 297 342
13 231 175 197 258
mean 240 155 180 230
median 231 138 160 216
SD 83 56 62 67
Range 117–386 92–265 112–297 143–342
  1. (Volumes of conventional PTV2 and simulated PTVs based on FET uptake at baseline (FET-1) expanded by 5, 7 and 10 mm margin in ml. The PTV include an additional margin of 5 mm around the CTV which is standardly used to compensate the set-up- and immobilisation uncertainties)
  2. PTV Planning Target Volume
  3. FET-1: pathological FET-Volume in ml at baseline (post surgery)
  4. MRI-1:Gd-contrast-enhancement in ml at baseline (post surgery)
  5. SD Standard Deviation