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Table 4 Recurrences in patients treated with chemoradiotherapy

From: Prognostic factors in clinical T1N0M0 thoracic esophageal squamous cell carcinoma invading the muscularis mucosa or submucosa

PS

Location

ER

RT field

Dose

Recurrence site

DFS

Treatment for recurrence

0

Mt

ENI

60.0

Local

0

Surgery

1

Mt

+

ENI

28.0

Lung

6.1

Surgery

0

Ut

Non-ENI

40.0

Local

7.2

ESD

0

Mt

+

ENI

40.0

#104R

13.1

Chemotherapy

0

Lt

+

ENI

39.6

#3, #7

15.3

Surgery

0

Ut

+

ENI

50.4

#101R

19.8

Chemotherapy

0

Mt

+

ENI

40.0

#109R

22.5

Chemotherapy

0

Mt

+

ENI

39.6

#104R

28.5

Chemotherapy

0

Mt

+

ENI

65.0

#104R

30.7

Chemotherapy

0

Mt

+

Non-ENI

40.0

#104R

31.0

Chemotherapy

0

Mt

+

ENI

39.6

Local

43.2

ESD

1

Lt

Non-ENI

65.0

#106recR

58.3

Chemotherapy

0

Mt

+

ENI

40.0

Local

75.1

ESD

  1. Lymph node metastasis was recorded according to the Japanese Society for Esophageal Diseases classification of esophageal cancer, 10th edition. #104: supraclavicular LNs (lymph nodes), #3: LNs along the lesser curvature, #7: LNs along the left gastric artery, #101: cervical paraesophageal LNs, #109: main bronchus LNs, #106rec: recurrent nerve LNs. DFS disease-free survival (months), Dose radiotherapy dose (Gy), ER endoscopic resection, ESD endoscopic submucosal dissection, Lt lower thoracic esophagus, Mt middle thoracic esophagus, PS Performance status, RT field radiotherapy field, Ut upper thoracic esophagus