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Table 3 Multivariate analysis for disease-specific survival and disease-free survival rates

From: Prognostic factors in clinical T1N0M0 thoracic esophageal squamous cell carcinoma invading the muscularis mucosa or submucosa

  Disease-specific survival Disease-free survival
Characteristics HR (95 % CI) p-value HR (95 % CI) p-value
Performance status
 0 1 <0.001* 1 <0.001*
  ≥ 1 8.72 (2.76–27.59)   5.31 (2.40–11.78)  
Radiation dose
  ≤ 50 Gy 1   1 0.618
  > 50 Gy 2.15 (0.46–10.07) 0.331 1.31 (0.45–3.81)  
Endoscopic resection
 No 1 0.268 1 0.656
 Yes 2.67 (0.47–15.20)   1.31 (0.40–4.30)  
Chemotherapy
 No 1 0.032 1 0.184
 Yes 0.29 (0.092–0.90)   0.59 (0.27–1.29)  
  1. HR hazard ratio, CI confidential interval, ENI elective nodal irradiation, RT radiotherapy. *Indicates significance after adjustment with Bonferroni correction (p-value < 0.0125)