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Table 3 Multivariate analysis for disease-specific survival and disease-free survival rates

From: Prognostic factors in clinical T1N0M0 thoracic esophageal squamous cell carcinoma invading the muscularis mucosa or submucosa

 

Disease-specific survival

Disease-free survival

Characteristics

HR (95 % CI)

p-value

HR (95 % CI)

p-value

Performance status

 0

1

<0.001*

1

<0.001*

  ≥ 1

8.72 (2.76–27.59)

 

5.31 (2.40–11.78)

 

Radiation dose

  ≤ 50 Gy

1

 

1

0.618

  > 50 Gy

2.15 (0.46–10.07)

0.331

1.31 (0.45–3.81)

 

Endoscopic resection

 No

1

0.268

1

0.656

 Yes

2.67 (0.47–15.20)

 

1.31 (0.40–4.30)

 

Chemotherapy

 No

1

0.032

1

0.184

 Yes

0.29 (0.092–0.90)

 

0.59 (0.27–1.29)

 
  1. HR hazard ratio, CI confidential interval, ENI elective nodal irradiation, RT radiotherapy. *Indicates significance after adjustment with Bonferroni correction (p-value < 0.0125)