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Table 2 Univariate analysis for disease-specific survival and disease-free survival rates

From: Prognostic factors in clinical T1N0M0 thoracic esophageal squamous cell carcinoma invading the muscularis mucosa or submucosa

 

n

5-year DSS (%)

p-value

5-year DFS (%)

p-value

Age

  ≤ 70

37

77.8

0.574

55.4

0.117

  > 70

34

65.7

 

44.3

 

Sex

 Male

57

70.9

0.925

49..7

0.917

 Female

14

76.2

 

51.9

 

Performance status

 0

57

78.8

<0.001

60.7

<0.001

  ≥ 1

14

53.8

 

0

 

Main tumor location

 Upper thoracic

12

0

0.205

64.8

0.186

 Middle thoracic

41

80.1

 

57.2

 

 Lower thoracic

18

74.9

 

25.5

 

RT field

 Non-ENI

32

62.3

0.094

42.0

0.389

 ENI

39

81.7

 

55.3

 

Radiation dose

  ≤ 50 Gy

32

88.5

0.003

61.6

0.035

  > 50 Gy

39

55.0

 

38.0

 

Tumor length

  ≤ 5 cm

55

70.5

0.540

50.9

0.818

  > 5 cm

16

85.2

 

50.6

 

Circumferential spread of tumor

  ≤ 0.75

63

71.2

0.464

47.7

0.302

  > 0.75, ≤1

8

83.3

 

68.6

 

Tumor number

 1

65

62.8

0.170

51.2

0.149

  ≥ 2

6

100

 

44.4

 

Depth of tumor invasion

 Muscularis mucosa

6

100

0.227

26.7

0.808

 Submucosa

65

70.7

 

51.3

 

Endoscopic resection

 No

26

53.6

0.005

33.8

0.014

 Yes

45

82.9

 

58.8

 

Chemotherapy

 No

24

54.5

0.005

44.1

0.036

 Yes

47

80.8

 

53.7

 
  1. DSS disease-specific survival, DFS disease-free survival, ENI elective nodal irradiation, RT radiotherapy