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Table 2 Univariate analysis for disease-specific survival and disease-free survival rates

From: Prognostic factors in clinical T1N0M0 thoracic esophageal squamous cell carcinoma invading the muscularis mucosa or submucosa

  n 5-year DSS (%) p-value 5-year DFS (%) p-value
Age
  ≤ 70 37 77.8 0.574 55.4 0.117
  > 70 34 65.7   44.3  
Sex
 Male 57 70.9 0.925 49..7 0.917
 Female 14 76.2   51.9  
Performance status
 0 57 78.8 <0.001 60.7 <0.001
  ≥ 1 14 53.8   0  
Main tumor location
 Upper thoracic 12 0 0.205 64.8 0.186
 Middle thoracic 41 80.1   57.2  
 Lower thoracic 18 74.9   25.5  
RT field
 Non-ENI 32 62.3 0.094 42.0 0.389
 ENI 39 81.7   55.3  
Radiation dose
  ≤ 50 Gy 32 88.5 0.003 61.6 0.035
  > 50 Gy 39 55.0   38.0  
Tumor length
  ≤ 5 cm 55 70.5 0.540 50.9 0.818
  > 5 cm 16 85.2   50.6  
Circumferential spread of tumor
  ≤ 0.75 63 71.2 0.464 47.7 0.302
  > 0.75, ≤1 8 83.3   68.6  
Tumor number
 1 65 62.8 0.170 51.2 0.149
  ≥ 2 6 100   44.4  
Depth of tumor invasion
 Muscularis mucosa 6 100 0.227 26.7 0.808
 Submucosa 65 70.7   51.3  
Endoscopic resection
 No 26 53.6 0.005 33.8 0.014
 Yes 45 82.9   58.8  
Chemotherapy
 No 24 54.5 0.005 44.1 0.036
 Yes 47 80.8   53.7  
  1. DSS disease-specific survival, DFS disease-free survival, ENI elective nodal irradiation, RT radiotherapy