Skip to main content

Table 1 Patients, tumor and treatment characteristics

From: Hypo-fractionated stereotactic radiotherapy alone using volumetric modulated arc therapy for patients with single, large brain metastases unsuitable for surgical resection

Patients N. 102 %
Gender
 Female 39 38
 Male 63 62
Age (median) 61 years (range 30–93 years)  
Histology
 Breast Cancer 18 17
 NSCLC 57 56
 Melanoma 12 12
 Other (CCC, Colon) 15 15
Stage at diagnosis of primary tumor
 I–III 51 50
 IV 51 50
KPS at BM diagnosis
 100 18 17
 90 18 17
 80 63 63
 70 3 3
RPA class
 I 18 18
 II 81 79
 III 3 3
GPA score 0–1 1.5–2.5 3 3.5–4  
Breast cancer 0 6 12 0  
NSCLC 12 36 3 6  
Melanoma 0 0 6 6  
Other 0 12 3 0  
Other extracranial metastatic site at diagnosis of BM 66 65
BM median maximum diameter cm (range cm) 2.9 (2.1–5)  
BM diameter cm   
2.1–3 cm 51 50
3.1–5 cm 51 50
GTV median volume cm3 (range cm3) 16.3 (3.9–64.5)  
PTV median volume cm3 (range cm3) 33.7 (9.2–122.3)  
HSRS Total dose/dose per fraction/n fractions   
27 Gy/9 Gy/3 51 50
32 Gy/8 Gy/4 51 50