From: Renal atrophy after stereotactic body radiotherapy for renal cell carcinoma
Parameters | Correlation of irradiated kidney | |||
---|---|---|---|---|
Variables | Median | Range | Correlation coefficient | P value |
V5 (%) | 73.7 | 43.3–91.8 | −0.44 | 0.11 |
V10 (%) | 67.3 | 34.7–82.5 | −0.56 | 0.03* |
V15 (%) | 62.5 | 28.8–67.9 | −0.68 | < .01* |
V20 (%) | 53.5 | 24.1–64.6 | −0.76 | < .01* |
V25 (%) | 46.8 | 20.8–61.1 | −0.77 | < .01* |
V30 (%) | 41.9 | 18.3–55.4 | −0.71 | < .01* |
V40 (%) | 33.8 | 14.5–47.5 | −0.65 | 0.01* |
V50 (%) | 20.7 | 6.3–42.1 | −0.43 | 0.12 |
V60 (%) | 13.6 | 0–35.5 | −0.19 | 0.49 |
Mean irradiated kidney dose (Gy) | 27.5 | 12.9–37.6 | −0.66 | < .01* |
Pre-SBRT irradiated renal volume (cc) | 160.4 | 99.4–295.5 | 0.07 | 0.79 |
GTV (cc) | 14.8 | 3.0–55.6 | 0.39 | 0.16 |
PTV (cc) | 79.8 | 28.1–146.9 | −0.03 | 0.91 |
Magnitude of overlap between PTV and kidney volume (cc) | 19.8 | 7.9–50.3 | −0.56 | 0.03* |
post-treatment contralateral kidney volume in percent (%, n = 12) | 99.3 | 89.4–109.0 | 0.65 | 0.02* |
Isocenter dose (Gy) | 68.8 | 50.0–76.4 | 0.07 | 0.80 |
Age (years) | 75 | 58–87 | 0.03 | 0.89 |
Creatinine change ratio (peak value/pre-SBRT) (%) | 139.5 | 105.7–190.0 | 0.32 | 0.26 |