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Table 4 Spearman’s correlations of the local control with the biologically effective dose at the isocenter and the planning target volume edge, calculated with different α/β values, for the complete dataset and exclusively for the hypofractionated dataset (all of them significant, p > 0.05)

From: Challenges in radiobiological modeling: can we decide between LQ and LQ-L models based on reviewed clinical NSCLC treatment outcome data?

Spearman’s r

vs BED @ Isocenter

vs BED @ PTV edge

α/β [Gy]

All datasets

HF

All datasets

HF

5

0.706

0.575

0.680

0.531

8.6

0.716

0.587

0.680

0.560

10

0.716

0.587

0.638

0.542

15

0.749

0.601

0.572

0.606

20

0.706

0.618

0.510

0.601

  1. BED biologically effective dose, PTV planning target volume