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Table 4 Spearman’s correlations of the local control with the biologically effective dose at the isocenter and the planning target volume edge, calculated with different α/β values, for the complete dataset and exclusively for the hypofractionated dataset (all of them significant, p > 0.05)

From: Challenges in radiobiological modeling: can we decide between LQ and LQ-L models based on reviewed clinical NSCLC treatment outcome data?

Spearman’s r vs BED @ Isocenter vs BED @ PTV edge
α/β [Gy] All datasets HF All datasets HF
5 0.706 0.575 0.680 0.531
8.6 0.716 0.587 0.680 0.560
10 0.716 0.587 0.638 0.542
15 0.749 0.601 0.572 0.606
20 0.706 0.618 0.510 0.601
  1. BED biologically effective dose, PTV planning target volume