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Table 2 Multivariate adjusted hazard ratio for death in nasopharyngeal cancer patients (n = 3605)

From: The impact of time factors on overall survival in patients with nasopharyngeal carcinoma: a population-based study

  Events/total (%) Adjusted hazard ratiod 95 % CIc p value
Wait time and duration of RTb     0.053
 Wait time ≤ 4 weeks, duration of RT ≤ 10 weeks 223/1946 (11.5) 1   
 Wait time > 4 weeks, duration of RT ≤ 10 weeks 75/255 (29.4) 1.26 (0.95–1.67) 0.097
 Wait time ≤ 4 weeks, duration of RT > 10 weeks 177/1342 (13.2) 1.04 (0.85–1.27) 0.683
 Wait time > 4 weeks, duration of RT > 10 weeks 24/62 (38.7) 1.70 (1.10–2.60) 0.015
Hospital ownership     0.183
 For profit 135/1127 (12.0) 1   
 Non-profit 273/1915 (14.3) 1.13 (0.91–1.40) 0.238
 Public 91/563 (16.2) 1.28 (0.98–1.67) 0.069
Hospital teaching level     0.552
 Medical center 313/2332 (13.4) 1   
 Regional 162/1121 (14.5) 1.11 (0.91–1.36) 0.278
 District 24/152 (15.8) 1.01 (0.66–1.55) 0.948
Gender     
 Male 387/2711 (14.3) 1   
 Female 112/894 (12.5) 0.98 (0.79–1.22) 0.900
Age group     <0.001
 0–44.99 years 108/1239 (8.7) 1   
 45–64.99 years 240/1916 (12.5) 1.25 (0.99–1.58) 0.052
 More than 65 years 151/450 (33.6) 2.65 (2.01–3.49) <0.001
Treatment     
 CCRTa 356/2970 (12.0) 1   
 RTb alone 143/635 (22.5) 1.58 (1.26–1.98) <0.001
Charlson Comorbidity Index Score (mean = 0.3778)     
 Lower than mean 104/2597 (4.0) 1   
 Higher than mean 395/1008 (39.2) 15.34 (12.26–19.18) <0.001
Urbanization     0.598
 Urban 138/1149 (12.0) 1   
 Suburban 198/1508 (13.1) 0.90 (0.72–1.12) 0.374
 Rural 163/948 (17.2) 0.89 (0.70–1.13) 0.372
  1. a CCRT concurrent chemoradiotherapy, b RT, radiotherapy
  2. c95 % CI, 95 % confidence interval
  3. dAdjusted for patient age, wait time, length of radiotherapy, gender, treatment, urbanization, Charlson Comorbidity Index Score, and hospital characteristics