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Table 4 The previous studies on grade 4 or 5 pneumonitis after radiation therapy in patients with interstitial pneumonitis

From: The clinical results of proton beam therapy in patients with idiopathic pulmonary fibrosis: a single center experience

  Number of patients Treatment Median total dose Pneumonitis
Yamaguchi et al. [7] 16 SBRT 48 3 (19 %)
Yamashita et al. [8] 13 SBRT 48 7 (53.8 %)
Lee et al. [9] 15 Conformal RT 56.9 5 (33.3 %)
Present study 16 PBT 80 Gy (RBE) 1 (6.3 %)
  1. Abbreviations: SBRT stereotactic body radiotherapy, RT radiotherapy, RBE relative biological dose effectiveness, PBT proton beam therapy