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Table 2 The grade of pneumonitis and respiratory function deterioration

From: The clinical results of proton beam therapy in patients with idiopathic pulmonary fibrosis: a single center experience

 

Age

Grade of pneumonitis

Pre FHJ

Post FHJ

MLD

Lung V20

Operable/inoperable

IPF treatment before PBT

IPF treatment after PBT

Deterioration of IPF shadow

1

69

1

1

3

8.1

14.8

Inoperable

-

HOT

+

2

77

1

2

2

3.7

5.7

Operable

-

-

-

3

85

1

1

2

5.6

9.1

Inoperable

-

-

-

4

66

1

2

3

6.3

10.4

Inoperable

-

-

+

5

78

3

3

4

4.2

6.9

Inoperable

-

HOT

+

6

71

2

2

2

3.0

4.7

Inoperable

Steroid

Steroid

-

7

75

1

1

1

9.4

16.1

Inoperable

-

-

+

8

83

1

1

1

0.9

4.2

Inoperable

-

-

-

9

89

5

1

3

10.6

17.9

Inoperable

-

HOT

+

10

63

1

1

1

6.8

12.8

Inoperable

Steroid

Steroid

+

11

80

1

1

3

4.2

6.9

Inoperable

-

HOT

+

12

69

1

1

3

3.8

6.3

Inoperable

-

HOT

-

13

72

1

4

4

1.8

2.9

Inoperable

HOT

HOT

-

14

75

1

2

2

8.7

14.6

Inoperable

-

-

-

15

77

1

1

1

4.7

8.5

Operable

-

-

-

16

79

1

4

4

3.4

5.5

Inoperable

HOT

HOT

-

  1. Abbreviations: Pre FHJ Fletcher-Hugh-Jones classification before proton beam therapy, Post FHJ Fletcher-Hugh-Jones classification after proton beam therapy, MLD mean lung dose, IPF idiopathic pulmonary fibrosis, HOT home oxygen therapy