Whole brain radiotherapy with adjuvant or concomitant boost in brain metastasis: dosimetric comparison between helical and volumetric IMRT technique

Borghetti, Paolo; Pedretti, Sara; Spiazzi, Luigi; Avitabile, Rossella; Urpis, Mauro; Foscarini, Federica; Tesini, Giulia; Trevisan, Francesca; Ghirardelli, Paolo; Pandini, Sara Angela; Triggiani, Luca; Magrini, Stefano Maria; Buglione, Michela

doi:10.1186/s13014-016-0634-6

Table 4 Dosimetric parameters of SIB plans

From: Whole brain radiotherapy with adjuvant or concomitant boost in brain metastasis: dosimetric comparison between helical and volumetric IMRT technique

	Technique	PTV	Brain-PTV				CI	HI	CN	Time (seconds)
Patient	Technique	D95% (Gy)/%	Dmean (Gy)	V35 (%)	V40 (%)	V45 (%)	CI	HI	CN	Time (seconds)
1	Helical IMRT-SIB	44.4/98.6	30.6	2.4	0.85	0.00	1.61	0.02	0.31	980
	VMAT-SIB	44.3/98.4	31.5	3.0	1.03	0.04	1.83	0.07	0.67	277
2	Helical IMRT-SIB	44.8/99.6	31.5	12.6	5.9	0.13	4.79	0.02	0.49	247
	VMAT-SIB	45.1/100.3	31.3	3.6	1.14	0.10	2.12	0.09	0.74	193
3	Helical IMRT-SIB	43.9/97.6	31.2	14.4	5.4	0.00	2.09	0.04	0.27	409
	VMAT-SIB	42.8/95.0	29.8	3.4	0.83	0.01	1.11	0.16	0.68	168
4	Helical IMRT-SIB A	43.5/96.6	31.8	10.7	3.4	0.00	6.03	0.05	2.00	480
	Helical IMRT-SIB B	43.4/96.5	31.8	10.7	3.4	0.00	0.36	0.06	0.07	480
	VMAT-SIB A	43.6/96.8	32.3	16.9	5.6	0.79	8.06	0.13	3.13	195
	VMAT-SIB B	44.9/99.7	32.3	16.9	5.6	0.79	1.68	0.12	0.71	195
5	Helical IMRT-SIB	44.6/99.1	31.4	4.3	1.55	0.00	1.83	0.02	0.46	485
	VMAT-SIB	44.9/99.8	31.9	3.6	1.34	0.07	3.84	0.06	0.22	237
6	Helical IMRT-SIB	44.2/98.3	31.3	4.0	0.93	0.00	1.69	0.04	0.41	401
	VMAT-SIB	44.9/99.7	31.0	2.6	1.06	0.06	2.08	0.05	0.73	235
7	Helical IMRT-SIB	44.2/98.2	30.5	3.3	1.00	0.00	1.38	0.03	0.34	276
	VMAT-SIB	43.1/95.8	31.3	2.8	0.90	0.00	1.11	0.05	0.00	247
8	Helical IMRT-SIB A	43.8/97.3	31.6	13.6	6.9	0.05	1.77	0.05	0.49	366
	Helical IMRT-SIB B	44.4/98.6	31.6	13.6	6.9	0.05	3.57	0.02	0.28	366
	VMAT-SIB A	42.3/94.0	29.9	3.5	0.80	0.00	1.11	0.07	0.02	149
	VMAT-SIB B	43.3/96.1	29.9	3.5	0.80	0.00	1.58	0.04	0.01	149
9	VMAT-SIB	43.3/99.3	30.3	1.5	0.50	0.00	1.19	0.05	0.15	133
	Helical IMRT-SIB	44.7/96.1	30.5	3.0	1.30	0.01	2.45	0.02	0.61	372
10	Helical IMRT-SIB A	44.7/99.3	31.0	8.2	3.6	0.00	2.12	0.02	0.54	384
	Helical IMRT-SIB B	44.5/98.9	31.0	8.2	3.6	0.00	1.98	0.03	0.49	384
	VMAT-SIB A	40.9/90.9	30.4	2.4	0.45	0.00	0.98	0.12	0.15	267
	VMAT-SIB B	43.3/96.3	30.4	2.4	0.45	0.00	1.32	0.05	0.15	267
	Helical IMRT-SIB (mean)	44.24	31.15	7.65	3.08	0.02	2.44	0.03	0.52	440.00
	VMAT-SIB (mean)	43.57	30.96	4.32	1.37	0.11	2.15	0.08	0.57	210.10
	p T student	ns	ns	ns	ns	ns	ns	0.000	ns	0.004

Legend: Patients number 4, 8 and 10 had two brain metastases, volume and the dosimetric parameters of each lesion (A and B) are reported in the table

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