Table 1 Inclusion and exclusion criteria

• Age between 50 and 70 years

• Women surgically treated for left or right breast cancer and for whom adjuvant treatment is radiotherapy with irradiation of the breast or chest wall irradiation and possibly ganglion chains,

• Adjuvant radiotherapy with 3D CRT performed in Clinique Pasteur Toulouse

• WHO performance status ECOG (Eastern Cooperative Oncology Group - index usually used to describe the patient's condition) = 0 or 1

• Being volunteer to participate in the study and having signed the consent form

• Indication of adjuvant chemotherapy

• Clinically or radiologically detectable metastasis

• Personal history of coronary artery disease or myocardial disease

• Personal history of breast cancer or other cancer requiring radiotherapy to the thorax

• Patient with controlled infection or severe disease and/or non-hazardous to their participation in the study

• Contraindications to injection of iodinated contrast (for CCTA): pregnancy, renal failure, allergy

• Pregnancy, lactation

• Abnormal echocardiography before radiotherapy:

 - LVEF <50 %

 - Longitudinal strain > − 16 %

 - Longitudinal strain rate <1 %/s

 - Abnormal wall motion

• CCTA before radiotherapy showing that therapeutic management is required (by decision of the radiologist and cardiologist)