Table 4 Gene-set analysis with TO and MI predictors using DAVID (https://david.ncifcrf.gov/)
From: Predicting multi-class responses to preoperative chemoradiotherapy in rectal cancer patients
Predictors | GO | Term | P-value | Genes |
|---|---|---|---|---|
TO | GO:0030334 | Regulation of cell migration | 0.046 | BCAR1, RRAS, BDKRB1, APC |
GO:0048469 | Cell maturation | 0.049 | HES1, TFCP2L1, MTCH1 | |
GO:0043065 | Positive regulation of apoptosis | 0.052 | IFNA2, OBSCN, GSDMA, MTCH1, RPS27A, APC | |
HSA00510 | N-Glycan biosynthesis | 0.021 | MGAT1, RFT1, GANAB | |
MI | GO:0008104 | Protein localization | 0.010 | SFT2D2, BLZF1, KIFAP3, BCAP29, NECAP1, GOSR1, SEC62, NSF, SRP9 |
GO:0015031 | Protein transport | 0.015 | SFT2D2, BLZF1, BCAP29, NECAP1, GOSR1, SEC62, NSF, SRP9 | |
GO:0045184 | Establishment of protein localization | 0.016 | SFT2D2, BLZF1, BCAP29, NECAP1, GOSR1, SEC62, NSF, SRP9 | |
HSA04114 | Oocyte meiosis | 0.051 | CCNE2, RPS6KA6, ITPR2 |