Short-course PET based simultaneous integrated boost for locally advanced cervical cancer

Radiation Oncology

Table 1 Overall dose volume histogram parameters for OARs

		Bladder			Rectum			Sigmoid			Bowel^*
Plan/Param		V_30Gy [%]	V_45Gy [%]	D_2cc [Gy]	V_30Gy [%]	V_45Gy [%]	D_2cc [Gy]	V_30Gy [%]	V_45Gy [%]	D_2cc [Gy]	V_30Gy [cm³]	V_45Gy [cm³]	D_2cc [Gy]
VMAT	Stand.	81.3 ± 2.2	48.0 ± 2.2	51.2 ± 0.1	90.8 ± 1.5	72.1 ± 1.9	50.9 ± 0.1	96.0 ± 1.3	75.0 ± 4.4	51.0 ± 0.1	448 ± 56	218 ± 31	51.7 ± 0.1
VMAT	SIB	83.5 ± 2.3^†	48.7 ± 2.3	51.9 ± 0.3^†	91.1 ± 1.5	73.1 ± 2.0^†	51.4 ± 0.2^†	96.6 ± 1.4	75.3 ± 4.4	51.1 ± 0.1	452 ± 59	220 ± 31	51.8 ± 0.2
IMPT	Stand.	60.1 ± 2.4	44.3 ± 2.3	51.0 ± 0.1	84.7 ± 1.7	70.3 ± 1.7	50.9 ± 0.1	87.7 ± 3.6	74.1 ± 4.0	50.8 ± 0.1	313 ± 44	206 ± 30	51.3 ± 0.1
IMPT	SIB	60.8 ± 2.4^†	45.1 ± 2.3^†	51.2 ± 0.2^†	85.2 ± 1.7^†	71.0 ± 1.8^†	51.2 ± 0.2^†	88.2 ± 3.5	74.4 ± 4.0	50.9 ± 0.1	316 ± 45^†	208 ± 31^†	51.6 ± 0.3

Dose volume histogram parameters comparing the overall treatment following the short-course concept to a standard fractionated schedule
Values are mean ± standard deviation of the mean
Abbreviations: Stand standard plan of 1.8Gy X 28, SIB sum of 10 fraction SIB and 18 fraction standard plan
^*Entire potential space within irradiated area,
^†Significant pair wise difference between Stand and SIB parameter

ISSN: 1748-717X