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Table 2 Quality Adjusted Life Expectancies [years] for different types of patients, and two different physician beliefs in the curative ability of lymph node irradiation

From: Personalized treatment planning with a model of radiation therapy outcomes for use in multiobjective optimization of IMRT plans for prostate cancer

Patient preference

Age

Risk group

PO a

WP\(^{b}_{65\,\%}\)

WP\(^{c}_{20\,\%}\)

Optimal choice d

Min-complications

60

intermediate

12.0

11.4

11.0

PO

 

60

high

9.4

9.9

8.8

MD

 

75

intermediate

7.1

6.7

6.4

PO

 

75

high

5.8

5.9

5.3

MD

Population average

60

intermediate

12.3

12.6

12.1

MD

 

60

high

9.8

11.1

10.0

WP

 

75

intermediate

7.2

7.3

7.1

MD

 

75

high

6.0

6.6

6.1

WP

Max life

60

intermediate

12.5

13.1

12.7

WP

 

60

high

9.9

11.7

10.5

WP

 

75

intermediate

7.3

7.7

7.4

WP

 

75

high

6.1

7.0

6.3

WP

  1. aPO = prostate-only RT
  2. b WP65 % = whole pelvic RT assuming a 65% cure rate for occult lymph node disease
  3. c WP20 % = whole pelvic RT assuming a 20% cure rate for occult lymph node disease
  4. dMD = optimal choice depends upon physician belief in efficacy of nodal irradiation
  5. Patients are stratified by age, disease risk group and attitude towards the balance between quantity and quality of life