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Table 1 Comparison of mean dose to organs at risk for IMRT delivered alone or matched to proton therapy to the primary tumor site

From: Acute toxicity in comprehensive head and neck radiation for nasopharynx and paranasal sinus cancers: cohort comparison of 3D conformal proton therapy and intensity modulated radiation therapy

 

Node negative

 

Node positive

 

Organ at risk

Alone (n = 2)

Matched (n = 8)

P

Alone (n = 10)

Matched (n = 6)

P

Oral Cavity

44.4

28.3

0.036

47.6

39.7

0.093

Larynx

46.3

38.9

0.117

43.5

46.2

0.492

Esophagus

26.0

29.4

0.296

35.6

36.8

0.562

Better spared parotid

31.6

26.5

0.192

32.9

35.3

>0.99

Lesser spared parotid

29.5 (n = 1)

28.8 (n = 8)

N/A

35.7 (n = 3)

37.2 (n = 3)

>0.99

  1. IMRT intensity modulated radiation therapy, radiation dose expressed in Gy