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Table 1 Comparison of mean dose to organs at risk for IMRT delivered alone or matched to proton therapy to the primary tumor site

From: Acute toxicity in comprehensive head and neck radiation for nasopharynx and paranasal sinus cancers: cohort comparison of 3D conformal proton therapy and intensity modulated radiation therapy

  Node negative   Node positive  
Organ at risk Alone (n = 2) Matched (n = 8) P Alone (n = 10) Matched (n = 6) P
Oral Cavity 44.4 28.3 0.036 47.6 39.7 0.093
Larynx 46.3 38.9 0.117 43.5 46.2 0.492
Esophagus 26.0 29.4 0.296 35.6 36.8 0.562
Better spared parotid 31.6 26.5 0.192 32.9 35.3 >0.99
Lesser spared parotid 29.5 (n = 1) 28.8 (n = 8) N/A 35.7 (n = 3) 37.2 (n = 3) >0.99
  1. IMRT intensity modulated radiation therapy, radiation dose expressed in Gy